# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3796209 | A | Drug metabolism in mouse brain assessed as ZL006 formation at 20 mg/kg, iv measured 15 to 30 mins post dosing by HPLC-MS/MS method | Mus musculus | 6 | ALA3792322 | organism-based format | Scientific Literature | |
2. | ALA3796216 | A | Metabolic stability in mouse plasma at 20 mg/kg, iv measured 15 to 30 mins post dosing by HPLC-MS/MS method | Mus musculus | 4 | ALA3792322 | organism-based format | Scientific Literature | |
3. | ALA3796218 | F | Protective activity in BCCAO-induced mouse acute cerebral ischemia model assessed as prolonged surviving time at 4 mg/kg, iv measured 1 hr post dose | Mus musculus | 3 | ALA3792322 | organism-based format | Scientific Literature | |
4. | ALA3796219 | F | Protective activity in BCCAO-induced mouse acute cerebral ischemia model assessed as prolonged surviving time at 4 mg/kg, iv measured 4 hrs post dose | Mus musculus | 2 | ALA3792322 | organism-based format | Scientific Literature | |
5. | ALA3796220 | F | Protective activity in iv dosed MCAO-induced rat focal cerebral ischemia model assessed as reduction in infarct size treated at 1 hr post reperfusion measured after 24 hrs by TTC-staining based analysis | Rattus norvegicus | 1 | ALA3792322 | organism-based format | Scientific Literature | |
6. | ALA3796221 | F | Protective activity in MCAO-induced rat focal cerebral ischemia model assessed as reduction in infarct size at 2 mg/kg, iv administered 1 hr post reperfusion measured after 24 hrs by TTC-staining based analysis | Rattus norvegicus | 1 | ALA3792322 | organism-based format | Scientific Literature | |
7. | ALA3796291 | F | Protective activity in MCAO-induced rat focal cerebral ischemia model assessed as reduction in infarct size at 1 mg/kg, iv administered 1 hr post reperfusion measured after 24 hrs by TTC-staining based analysis | Rattus norvegicus | 1 | ALA3792322 | organism-based format | Scientific Literature |