| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3796468 | A | AUC (0 to 24 hrs) in Sprague-Dawley rat at 10 mg/kg, iv by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA3796469 | B | Inhibition of human recombinant MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition by fluorimetric analysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 3. | ALA3796470 | B | Inhibition of human recombinant MMP9 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition by fluorimetric analysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 4. | ALA3796552 | B | Selectivity ratio of IC50 for human recombinant MMP9 to IC50 for human recombinant MMP2 | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 5. | ALA3796553 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, iv after 15 mins to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA3796554 | A | Apparent volume of distribution in Sprague-Dawley rat at 10 mg/kg, iv after 15 mins to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA3796555 | A | Terminal half life in Sprague-Dawley rat at 10 mg/kg, iv by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA3796556 | A | Apparent clearance in Sprague-Dawley rat at 10 mg/kg, iv after 15 mins to 24 hrs by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA3796557 | A | AUC (0 to 24 hrs) in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS method | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA3796558 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po after 15 mins to 24 hrs by LC-MS/MS method | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3796559 | A | Apparent volume of distribution in Sprague-Dawley rat at 10 mg/kg, po after 15 mins to 24 hrs by LC-MS/MS method | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3796560 | A | Terminal half life in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS method | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3796561 | A | Apparent clearance in Sprague-Dawley rat at 10 mg/kg, po after 15 mins to 24 hrs by LC-MS/MS method | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3796562 | F | Antiinvasive activity in human HEY cells assessed as reduction in number of cells invading matrigel membrane after 24 hrs by crystal violet staining-based Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3796563 | F | Antiinvasive activity in human HEY cells assessed as reduction in number of cells invading matrigel membrane at 50 uM after 24 hrs by crystal violet staining-based Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3796564 | A | Cytotoxicity against human HEY cells at 6.25 to 100 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3796565 | F | Antimigratory activity in human HEY cells after 24 hrs by crystal violet staining-based Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3796566 | F | Antimigratory activity in human HEY cells at 50 uM after 24 hrs by crystal violet staining-based Transwell assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3796567 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg by LC-MS/MS method | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA3796568 | P | Lipid-water partition coefficient, logP of compound | 2 | small-molecule physicochemical format | Scientific Literature |
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