# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3804199 | F | Agonist activity at human recombinant S1PR1 expressed in CHO cell membranes incubated for 30 mins by [35S]GTPgammaS binding assay in presence of GDP | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA3804200 | F | Agonist activity at human recombinant S1PR3 expressed in CHO cell membranes incubated for 30 mins by [35S]GTPgammaS binding assay in presence of GDP | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
3. | ALA3804201 | F | Decrease in peripheral blood lymphocyte count in Wistar rat at 10 mg/kg administered via oral gavage measured after 3 hrs | Rattus norvegicus | 21 | organism-based format | Scientific Literature | ||
4. | ALA3804202 | F | Decrease in peripheral blood lymphocyte count in Wistar rat at 10 mg/kg administered via oral gavage measured after 6 hrs | Rattus norvegicus | 21 | organism-based format | Scientific Literature | ||
5. | ALA3804203 | F | Decrease in peripheral blood lymphocyte count in Wistar rat at 10 mg/kg administered via oral gavage measured after 24 hrs | Rattus norvegicus | 21 | organism-based format | Scientific Literature | ||
6. | ALA3804205 | F | Decrease in peripheral blood lymphocyte count in Wistar rat at 10 mg/kg administered via oral gavage measured after 72 hrs | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
7. | ALA3804208 | A | Plasma concentration in Wistar rat at 10 mg/kg administered via oral gavage measured after 3 hrs by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
8. | ALA3804209 | A | Plasma concentration in Wistar rat at 10 mg/kg administered via oral gavage measured after 6 hrs by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
9. | ALA3804210 | A | Plasma concentration in Wistar rat at 10 mg/kg administered via oral gavage measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
10. | ALA3804211 | A | Plasma concentration in Wistar rat at 10 mg/kg administered via oral gavage measured after 72 hrs by LC-MS/MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA3801418 | F | Time duration of maximum lymphocyte count reduction in Wistar rat at 10 mg/kg administered via oral gavage | Rattus norvegicus | 21 | organism-based format | Scientific Literature | ||
12. | ALA3801419 | A | Half life in Wistar rat at 10 mg/kg administered via oral gavage by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
13. | ALA3801420 | F | Phototoxicity in Balb/c mouse 3T3 clone A31 cells assessed as AUC of UV spectra between 310 and 350 nm normalized to compound concentration at 0.05 to 100 uM preincubated for 1 hr followed by UVA irradiation measured after 24 hrs by neutral red uptake assay relative to control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
14. | ALA3801421 | F | Phototoxicity in Balb/c mouse 3T3 clone A31 cells assessed as inhibition of cell viability measured as photo irritancy factor at 0.05 to 100 uM preincubated for 1 hr followed by UVA irradiation measured after 24 hrs by neutral red uptake assay relative to control | Mus musculus | 17 | cell-based format | Scientific Literature | ||
15. | ALA4029473 | A | Induction of tracheal constriction in Wistar rat at 1 uM | Rattus norvegicus | 4 | assay format | Scientific Literature | ||
16. | ALA4029474 | A | Induction of tracheal constriction in Wistar rat at 10 uM | Rattus norvegicus | 3 | assay format | Scientific Literature |