# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3804199 | Functional | Agonist activity at human recombinant S1PR1 expressed in CHO cell membranes incubated for 30 mins by [35S]GTPgammaS binding assay in presence of GDP | Homo sapiens | 25 | ALA3797143 | cell-based format | Scientific Literature | |
2. | ALA3804200 | Functional | Agonist activity at human recombinant S1PR3 expressed in CHO cell membranes incubated for 30 mins by [35S]GTPgammaS binding assay in presence of GDP | Homo sapiens | 25 | ALA3797143 | cell-based format | Scientific Literature | |
3. | ALA3804201 | Functional | Decrease in peripheral blood lymphocyte count in Wistar rat at 10 mg/kg administered via oral gavage measured after 3 hrs | Rattus norvegicus | 21 | ALA3797143 | organism-based format | Scientific Literature | |
4. | ALA3804202 | Functional | Decrease in peripheral blood lymphocyte count in Wistar rat at 10 mg/kg administered via oral gavage measured after 6 hrs | Rattus norvegicus | 21 | ALA3797143 | organism-based format | Scientific Literature | |
5. | ALA3804203 | Functional | Decrease in peripheral blood lymphocyte count in Wistar rat at 10 mg/kg administered via oral gavage measured after 24 hrs | Rattus norvegicus | 21 | ALA3797143 | organism-based format | Scientific Literature | |
6. | ALA3801418 | Functional | Time duration of maximum lymphocyte count reduction in Wistar rat at 10 mg/kg administered via oral gavage | Rattus norvegicus | 21 | ALA3797143 | organism-based format | Scientific Literature | |
7. | ALA3801420 | Functional | Phototoxicity in Balb/c mouse 3T3 clone A31 cells assessed as AUC of UV spectra between 310 and 350 nm normalized to compound concentration at 0.05 to 100 uM preincubated for 1 hr followed by UVA irradiation measured after 24 hrs by neutral red uptake assay relative to control | Mus musculus | 12 | ALA3797143 | cell-based format | Scientific Literature | |
8. | ALA3801421 | Functional | Phototoxicity in Balb/c mouse 3T3 clone A31 cells assessed as inhibition of cell viability measured as photo irritancy factor at 0.05 to 100 uM preincubated for 1 hr followed by UVA irradiation measured after 24 hrs by neutral red uptake assay relative to control | Mus musculus | 17 | ALA3797143 | cell-based format | Scientific Literature |