Antihypertensive activity in anesthetized Wistar rat assessed as change in mean arterial blood pressure at 0.1 mg/kg, iv administered as bolus dose after 2 mins
Antihypertensive activity in anesthetized Wistar rat assessed as change in mean arterial blood pressure at 0.1 mg/kg, iv administered as bolus dose after 5 mins (Rvb = 0.4 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in mean arterial blood pressure at 0.1 mg/kg, iv administered as bolus dose after 15 mins (Rvb = -0.8 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in mean arterial blood pressure at 0.1 mg/kg, iv administered as bolus dose after 30 mins (Rvb = -1.3 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in mean arterial blood pressure at 0.1 mg/kg, iv administered as bolus dose after 60 mins (Rvb = -3.5 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in heart rate at 0.1 mg/kg, iv administered as bolus dose after 2 mins (Rvb = -0.6 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in heart rate at 0.1 mg/kg, iv administered as bolus dose after 5 mins (Rvb = -2.9 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in heart rate at 0.1 mg/kg, iv administered as bolus dose after 15 mins (Rvb = -6.0 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in heart rate at 0.1 mg/kg, iv administered as bolus dose after 30 mins (Rvb = -8.6 mmHg)
Antihypertensive activity in anesthetized Wistar rat assessed as change in heart rate at 0.1 mg/kg, iv administered as bolus dose after 60 mins (Rvb = -6.2 mmHg)