#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3801076	Functional	Antiproliferative activity against human p53 +/+ HCT116 cells measured after 72 hrs by MTS assay	Homo sapiens	32	ALA3797025	cell-based format	Scientific Literature
2.	ALA3801077	Functional	Antiproliferative activity against human p53 -/- HCT116 cells measured after 72 hrs by MTS assay	Homo sapiens	18	ALA3797025	cell-based format	Scientific Literature
3.	ALA3801078	Functional	Antiproliferative activity against human HepG2 cells expressing wild-type P53 measured after 72 hrs by MTS assay	Homo sapiens	9	ALA3797025	cell-based format	Scientific Literature
4.	ALA3801079	Functional	Antiproliferative activity against human SW620 cells expressing P53 mutant measured after 72 hrs by MTS assay	Homo sapiens	9	ALA3797025	cell-based format	Scientific Literature
5.	ALA3801080	Binding	Inhibition of p53-MDM2 interaction (unknown origin) in human p53 -/- HCT116 cells co-transfected with V1-p53/MDM2-V2 plasmid assessed as interaction-induced fluorescence level at 5 uM by Venus-based bimolecular fluorescence complementation assay (Rvb = 34.18 %)	Homo sapiens	2	ALA3797025	cell-based format	Scientific Literature
6.	ALA3801081	Binding	Inhibition of p53-MDM2 interaction (unknown origin) in human p53 -/- HCT116 cells co-transfected with V1-p53/MDM2-V2 plasmid interaction-induced fluorescence level at 10 uM by Venus-based bimolecular fluorescence complementation assay (Rvb = 34.18 %)	Homo sapiens	2	ALA3797025	cell-based format	Scientific Literature
7.	ALA3801279	Binding	Inhibition of p53-MDM2 interaction (unknown origin) in human p53 -/- HCT116 cells co-transfected with V1-p53/MDM2-V2 plasmid interaction-induced fluorescence level at 20 uM by Venus-based bimolecular fluorescence complementation assay (Rvb = 34.18 %)	Homo sapiens	2	ALA3797025	cell-based format	Scientific Literature
8.	ALA3801280	Binding	Induction of p53 stabilization in human p53 +/+ HCT116 cells assessed as increase in p53 level at 5 uM after 24 hrs by immunoblot analysis	Homo sapiens	2	ALA3797025	cell-based format	Scientific Literature
9.	ALA3801281	Binding	Induction of p53 stabilization in human p53 +/+ HCT116 cells assessed as increase in MDM2 level at 5 uM after 24 hrs by immunoblot analysis	Homo sapiens	2	ALA3797025	cell-based format	Scientific Literature
10.	ALA3801282	Binding	Induction of p53 transcriptional activation in human p53 +/+ HCT116 cells assessed as PUMA transactivation at 10 uM after 24 hrs by dual-luciferase reporter assay	Homo sapiens	2	ALA3797025	cell-based format	Scientific Literature
11.	ALA3801283	Binding	Induction of p53 transcriptional activation in human p53 +/+ HCT116 cells assessed as p21/WAF1 transactivation at 10 uM after 24 hrs by dual-luciferase reporter assay	Homo sapiens	2	ALA3797025	cell-based format	Scientific Literature
12.	ALA3801284	Functional	Induction of apoptosis in human p53 +/+ HCT116 cells assessed as activation of caspase3 at 5 or 10 uM after 24 hrs by Caspase-Glo 3/7 assay	Homo sapiens	1	ALA3797025	cell-based format	Scientific Literature
13.	ALA3801285	Functional	Induction of apoptosis in human p53 +/+ HCT116 cells assessed as activation of caspase7 at 5 or 10 uM after 24 hrs by Caspase-Glo 3/7 assay	Homo sapiens	1	ALA3797025	cell-based format	Scientific Literature
14.	ALA3801286	Functional	Induction of apoptosis in human p53 +/+ HCT116 cells assessed as increase in PARP cleavage at 5 or 10 uM after 24 hrs by western blot analysis	Homo sapiens	1	ALA3797025	cell-based format	Scientific Literature
15.	ALA3801287	Binding	Induction of p53 phosphorylation at serine-15 in human p53 +/+ HCT 116 cells bat 5 or 10 uM after 24 hrs by western blot analysis	Homo sapiens	1	ALA3797025	cell-based format	Scientific Literature
16.	ALA3801288	Physicochemical	Chemical stability in phosphate buffer at pH 7.4 and 37 degC measured for 3 days by HPLC analysis		1	ALA3797025	small-molecule physicochemical format	Scientific Literature
17.	ALA3801289	ADME	Metabolic stability at human plasma assessed as compound degradation at 37 degC after 72 hrs by HPLC analysis	Homo sapiens	1	ALA3797025	cell-free format	Scientific Literature
18.	ALA3801290	ADME	Half life in Sprague-Dawley rat liver microsomes at 37 degC in presence of NADPH generating system by HPLC analysis	Rattus norvegicus	1	ALA3797025	tissue-based format	Scientific Literature