# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3804623 | B | Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus (DE3)-RIL cells using MTOB as substrate after 15 mins by NADH consumption assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA3804624 | F | Cytotoxicity against human HCT116 p53-/- cells assessed as inhibition of cell growth after 72 hrs by MTT assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
3. | ALA3804625 | B | Inhibition of rabbit muscle L-lactate dehydrogenase using sodium pyruvate as substrate measured every 10 secs for 30 mins by microplate reader method | Oryctolagus cuniculus | 4 | assay format | Scientific Literature | ||
4. | ALA3804626 | B | Selectivity ratio of IC50 for rabbit muscle L-lactate dehydrogenase to IC50 for recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity | 3 | assay format | Scientific Literature | |||
5. | ALA3804627 | P | Aqueous stability in pH 7.2 phosphate buffer at 4 mM after 72 hrs by HPLC method | 3 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA3804628 | B | Inhibition of CtBP2 (unknown origin) transfected in human HCT116 p53-/- cells assessed as increase in Bik transcription at 2 mM by dual luciferase reporter gene assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA3804629 | B | Inhibition of CtBP2 (unknown origin) transfected in human HCT116 p53-/- cells assessed as increase in Bik transcription at 4 mM by dual luciferase reporter gene assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |