# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3802768 | Binding | Inhibition of human NAMPT using NAM as substrate assessed as NMN formation preincubated for 5 mins followed by substrate addition measured after 15 mins by fluorometric assay | Homo sapiens | 11 | ALA3797081 | single protein format | Scientific Literature | |
2. | ALA3804691 | ADME | Plasma protein binding in human | Homo sapiens | 2 | ALA3797081 | cell-free format | Scientific Literature | |
3. | ALA3804692 | ADME | Inhibition of CYP1A2 (unknown origin) at 3 uM relative to control | Homo sapiens | 2 | ALA3797081 | single protein format | Scientific Literature | |
4. | ALA3804693 | ADME | Inhibition of CYP2C9 (unknown origin) at 3 uM relative to control | Homo sapiens | 2 | ALA3797081 | single protein format | Scientific Literature | |
5. | ALA3804694 | ADME | Inhibition of CYP2D6 (unknown origin) at 3 uM relative to control | Homo sapiens | 2 | ALA3797081 | single protein format | Scientific Literature | |
6. | ALA3804695 | ADME | Inhibition of CYP3A4 (unknown origin) at 3 uM relative to control | Homo sapiens | 2 | ALA3797081 | single protein format | Scientific Literature | |
7. | ALA3804696 | ADME | Metabolic stability in human liver microsomes assessed as parent compound remaining at 5 uM measured at 30 mins in presence of NADPH | Homo sapiens | 2 | ALA3797081 | tissue-based format | Scientific Literature | |
8. | ALA3804697 | ADME | Metabolic stability in human liver microsomes assessed as parent compound remaining at 5 uM measured at 30 mins in absence of NADPH | Homo sapiens | 2 | ALA3797081 | tissue-based format | Scientific Literature | |
9. | ALA3804698 | ADME | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 5 uM measured at 30 mins in presence of NADPH | Mus musculus | 2 | ALA3797081 | tissue-based format | Scientific Literature | |
10. | ALA3804699 | ADME | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 5 uM measured at 30 mins in absence of NADPH | Mus musculus | 2 | ALA3797081 | tissue-based format | Scientific Literature | |
11. | ALA3804700 | ADME | Permeability across human Caco2 cells assessed as drug recovery | Homo sapiens | 2 | ALA3797081 | cell-based format | Scientific Literature |