| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3801109 | B | Selectivity ratio of IC50 for human LIMK1 to IC50 for human LIMK2 | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 2. | ALA3801110 | B | Inhibition of human LIMK1 using cofilin as substrate preincubated for 20 mins followed by [gamma-33P]-ATP/10 uM ATP addition measured after 120 mins by radiometric assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 3. | ALA3801111 | B | Inhibition of human LIMK2 using cofilin as substrate preincubated for 20 mins followed by [gamma-33P]-ATP/10 uM ATP addition measured after 120 mins by radiometric assay | Homo sapiens | 47 | single protein format | Scientific Literature | ||
| 4. | ALA3801112 | B | Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate preincubated for 20 mins followed by [gamma-33P]-ATP/10 uM ATP addition measured after 120 mins by radiometric assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA3801113 | B | Inhibition of human PKACA using GRTGRRNSI-NH2 as substrate preincubated for 20 mins followed by [gamma-33P]-ATP/10 uM ATP addition measured after 120 mins by radiometric assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA3801311 | B | Inhibition of human SIK2 at 300 nM using AMARAASAAALARRR as substrate preincubated for 20 mins followed by [gamma-33P]-ATP/10 uM ATP addition measured after 120 mins by radiometric assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3801312 | B | Inhibition of human RSK4 at 300 nM using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate preincubated for 20 mins followed by [gamma-33P]-ATP/10 uM ATP addition measured after 120 mins by radiometric assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3801313 | A | Apparent permeability from apical side at pH 6.5 to basolateral side at pH 7.4 in human Caco2 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA3801314 | A | Apparent permeability from apical to basolateral side in human Caco2 cells at pH 7.4 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA5244630 | B | Inhibition of LIMK2 (unknown origin) in presence of ATP at 200 uM | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 11. | ALA5244631 | B | Inhibition of human recombinant LIMK1 in presence of ATP cofilin as substrate at 25 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 12. | ALA5244632 | B | Inhibition of ROCK2 (unknown origin) by Kinase Glo luminescence assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 13. | ALA5244633 | B | Inhibition of LIMK1 (unknown origin) | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 14. | ALA5244634 | B | Selectivity index, ratio of IC50 for ROCK2 (unknown origin) to IC50 for PKA (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA5244635 | B | Inhibition of PKA (unknown origin) assessed as fold increase | Homo sapiens | 1 | protein format | Scientific Literature |
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