# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3804532 | Functional | Antimicrobial activity against Candida albicans CAF2-1 after 24 hrs by two fold serial dilution method | Candida albicans | 12 | ALA3797157 | organism-based format | Scientific Literature | |
2. | ALA3804533 | Functional | Antimicrobial activity against Candida glabrata after 24 hrs by two fold serial dilution method | Nakaseomyces glabratus | 12 | ALA3797157 | organism-based format | Scientific Literature | |
3. | ALA3804534 | Functional | Antimicrobial activity against Candida krusei ATCC 6258 after 24 hrs by two fold serial dilution method | Pichia kudriavzevii | 12 | ALA3797157 | organism-based format | Scientific Literature | |
4. | ALA3804535 | Functional | Antimicrobial activity against Candida tropicalis ATCC 75 after 24 hrs by two fold serial dilution method | Candida tropicalis | 12 | ALA3797157 | organism-based format | Scientific Literature | |
5. | ALA3804536 | Functional | Antimicrobial activity against Candida parapsilosis ATCC 22019 after 24 hrs by two fold serial dilution method | Candida parapsilosis | 12 | ALA3797157 | organism-based format | Scientific Literature | |
6. | ALA3804537 | Functional | Antimicrobial activity against Saccharomyces cerevisiae BY4741 after 24 hrs by two fold serial dilution method | Saccharomyces cerevisiae | 12 | ALA3797157 | assay format | Scientific Literature | |
7. | ALA3804538 | Functional | Antibiofilm activity against Candida albicans CAF2-1 assessed as reduction in metabolic activity after 48 hrs by XTT assay | Candida albicans | 12 | ALA3797157 | organism-based format | Scientific Literature | |
8. | ALA3804539 | Functional | Antimicrobial activity against Escherichia coli | Escherichia coli | 8 | ALA3797157 | organism-based format | Scientific Literature | |
9. | ALA3804540 | Functional | Antimicrobial activity against Pseudomonas aeruginosa | Pseudomonas aeruginosa | 8 | ALA3797157 | organism-based format | Scientific Literature | |
10. | ALA3804541 | Functional | Antimicrobial activity against Staphylococcus aureus | Staphylococcus aureus | 8 | ALA3797157 | organism-based format | Scientific Literature | |
11. | ALA3804542 | ADME | Cytotoxicity against human HeLa cells after 48 hrs by SRB assay | Homo sapiens | 12 | ALA3797157 | cell-based format | Scientific Literature | |
12. | ALA3804543 | Unassigned | Selectivity index, ratio of IC50 for human HeLa cells to MIC for Candida albicans CAF2-1 | 12 | ALA3797157 | cell-based format | Scientific Literature | ||
13. | ALA4704257 | Functional | Growth inhibition of amastigote form of Trypanosoma cruzi Tulahuen C2C4 expressing LacZ infected in rat L6 cells assessed as reduction in parasitic growth incubated for 96 hra by CPRG/Nonidet reagent based inverted microscopic analysis | Trypanosoma cruzi | 20 | ALA4699587 | organism-based format | Scientific Literature | |
14. | ALA4704258 | ADME | Cytotoxicity against rat L6 cells assessed as reduction in cell viability after 70 hrs by resazurin dye based inverted microscopic analysis | Rattus norvegicus | 21 | ALA4699587 | cell-based format | Scientific Literature | |
15. | ALA4704259 | Toxicity | Selectivity index, ratio of IC50 for cytotoxicity against rat L6 cells to IC50 for growth inhibition of amastigote form of Trypanosoma cruzi Tulahuen C2C4 expressing LacZ infected in rat L6 cells | 20 | ALA4699587 | cell-based format | Scientific Literature | ||
16. | ALA5230039 | Functional | Inhibition of NO production in LPS-stimulated mouse RAW264.7 cells at 50 uM preincubated for 15 mins followed by LPS stimulation and measured after 20 hrs by Griess reagent based assay relative to control | Mus musculus | 29 | ALA5226392 | cell-based format | Scientific Literature | |
17. | ALA5230041 | Toxicity | Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as cell survival at 50 uM preincubated for 15 mins followed by LPS stimulation and measured after 20 hrs by CCK-8 assay relative to control | Mus musculus | 29 | ALA5226392 | cell-based format | Scientific Literature | |
18. | ALA5230043 | Functional | Antiinflammatory activity in human 293/NFkB-Luc cells assessed as inhibition of TNF-alpha induced NFkaapaB activity at 50 uM preincubated for 15 mins followed by TNF-alpha induction and measured after 6 hrs by luminescence based assay relative to control | Homo sapiens | 29 | ALA5226392 | cell-based format | Scientific Literature | |
19. | ALA5230045 | Toxicity | Cytotoxicity against TNF-alpha induced human 293/NFkB-Luc cells assessed as increase in cell survival at 50 uM preincubated for 15 mins followed by TNF-alpha induction and measured after 6 hrs by MTT assay relative to control | Homo sapiens | 29 | ALA5226392 | cell-based format | Scientific Literature |