| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3801041 | B | Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA | Homo sapiens | 27 | ALA3797175 | single protein format | Scientific Literature | |
| 2. | ALA3801045 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv administered as single dose | Rattus norvegicus | 3 | ALA3797175 | organism-based format | Scientific Literature | |
| 3. | ALA3801047 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv administered as single dose | Rattus norvegicus | 3 | ALA3797175 | organism-based format | Scientific Literature | |
| 4. | ALA3801049 | A | Half life in Sprague-Dawley rat at 2 mg/kg, iv administered as single dose | Rattus norvegicus | 3 | ALA3797175 | organism-based format | Scientific Literature | |
| 5. | ALA3801051 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po administered as single dose | Rattus norvegicus | 4 | ALA3797175 | organism-based format | Scientific Literature | |
| 6. | ALA3801052 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po administered as single dose | Rattus norvegicus | 4 | ALA3797175 | organism-based format | Scientific Literature | |
| 7. | ALA3801053 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po administered as single dose | Rattus norvegicus | 4 | ALA3797175 | organism-based format | Scientific Literature | |
| 8. | ALA3801054 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg administered as single dose | Rattus norvegicus | 4 | ALA3797175 | organism-based format | Scientific Literature | |
| 9. | ALA3801055 | F | Antitumor activity against human EBC1 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 25 mg/kg, po bid for 21 days measured twice a week during compound dosing relative to control | Homo sapiens | 3 | ALA3797175 | organism-based format | Scientific Literature | |
| 10. | ALA3801246 | F | Antitumor activity against human EBC1 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 12.5 mg/kg, po bid for 21 days measured twice a week during compound dosing relative to control | Homo sapiens | 3 | ALA3797175 | organism-based format | Scientific Literature | |
| 11. | ALA3801247 | T | Toxicity in athymic nude mouse xenografted with human EBC1 cells assessed as increase in body weight at 12.5 to 25 mg/kg, po bid for 21 days measured twice a week during compound dosing | Mus musculus | 1 | ALA3797175 | organism-based format | Scientific Literature | |
| 12. | ALA3801249 | B | Inhibition of recombinant RON (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 13. | ALA3801250 | B | Inhibition of recombinant AXL (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 14. | ALA3801251 | B | Inhibition of recombinant TYRO3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 15. | ALA3801252 | B | Inhibition of recombinant c-Mer (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 16. | ALA3801253 | B | Inhibition of recombinant IGF1R (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 17. | ALA3801254 | B | Inhibition of recombinant ALK (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 18. | ALA3801255 | B | Inhibition of recombinant ROS1 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 19. | ALA3801256 | B | Inhibition of recombinant PDGFRalpha (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature | |
| 20. | ALA3801257 | B | Inhibition of recombinant PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 as substrate at 1000 nM incubated for 60 mins by ELISA relative to control | Homo sapiens | 1 | ALA3797175 | single protein format | Scientific Literature |
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