# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3803623 | B | Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins by fluorescence assay | Schistosoma mansoni | 41 | assay format | Scientific Literature | ||
2. | ALA3803862 | B | Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins by fluorescence assay | Homo sapiens | 41 | single protein format | Scientific Literature | ||
3. | ALA3803863 | B | Inhibition of recombinant human HDAC1 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins by fluorescence assay | Homo sapiens | 37 | single protein format | Scientific Literature | ||
4. | ALA3803864 | B | Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins by fluorescence assay | Homo sapiens | 40 | single protein format | Scientific Literature | ||
5. | ALA3801367 | F | Antiparasitic activity against schistosomula stage of Schistosoma mansoni assessed as parasite viability at 10 uM after 48 hrs by Alamar Blue assay relative to control | Schistosoma mansoni | 31 | organism-based format | Scientific Literature | ||
6. | ALA3801368 | F | Antiparasitic activity against schistosomula stage of Schistosoma mansoni assessed as parasite viability at 20 uM after 48 hrs by Alamar Blue assay relative to control | Schistosoma mansoni | 31 | organism-based format | Scientific Literature | ||
7. | ALA3801375 | A | Cytotoxicity against HEK293 cells assessed as cell viability at 50 uM after 24 hrs by Alamar Blue assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
8. | ALA4014727 | B | Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assay | Schistosoma mansoni | 168 | single protein format | Scientific Literature |