| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3804125 | B | Selectivity index, ratio of IC50 for wild type B-Raf (unknown origin) to IC50 for B-Raf V600E mutant (unknown origin) | Homo sapiens | 37 | assay format | Scientific Literature | ||
| 2. | ALA3804126 | B | Inhibition of wild type B-Raf (unknown origin) assessed as MEK1 phosphorylation using MEK1-Avitag as substrate after 1 hr by HTRF assay | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 3. | ALA3804127 | B | Inhibition of B-Raf V600E mutant (unknown origin) assessed as MEK1 phosphorylation using MEK1-Avitag as substrate after 1 hr by HTRF assay | Homo sapiens | 39 | single protein format | Scientific Literature | ||
| 4. | ALA3804128 | B | Inhibition of wild type B-Raf in human MIAPaCa2 cells assessed as reduction in ERK phosphorylation preincubated for 1 hr by Western blot method | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 5. | ALA3804129 | B | Inhibition of B-Raf V600E mutant in human A375 cells assessed as ERK phosphorylation preincubated for 1 hr by Western blot method | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 6. | ALA3804371 | B | Selectivity index, ratio of EC50 for wild type B-Raf in human MIAPaCa2 cells to IC50 for B-Raf V600E mutant in human A375 cells | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 7. | ALA3804372 | B | Inhibition of wild type B-Raf in human MIAPaCa2 cells assessed as induction of ERK phosphorylation preincubated for 1 hr by Western blot method relative to control | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 8. | ALA3804373 | B | Inhibition of partial length wild type human MEK5 expressed in mammalian system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA3804374 | B | Inhibition of partial length wild type human BRAF expressed in mammalian system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA3804375 | B | Inhibition of partial length wild type human BRK expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA3804376 | B | Inhibition of partial length wild type human RIPK2 expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA3804377 | B | Inhibition of full length wild type human LIMK1 expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA3804378 | B | Inhibition of partial length wild type human TIE2 expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA3804379 | B | Inhibition of partial length wild type human FYN expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA3804380 | B | Inhibition of partial length wild type human TGFBR1 expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA3804381 | B | Inhibition of partial length wild type human AURKA expressed in mammalian system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA3804382 | B | Inhibition of partial length wild type human KIT expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA3804383 | B | Inhibition of partial length wild type human PIK3CD expressed in mammalian system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA3804384 | B | Inhibition of full length wild type human GRK1 expressed in mammalian system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA3804385 | B | Inhibition of full length wild type human MKNK1 expressed in mammalian system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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