| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3803372 | B | Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysis | Mus musculus | 13 | cell-based format | Scientific Literature | ||
| 2. | ALA3803373 | B | Displacement of 125I-NDP-MSH from mouse MC1R expressed in HEK293 cells incubated for 1 hr by gamma counting analysis | Mus musculus | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA3803374 | B | Displacement of 125I-NDP-MSH from mouse MC3R expressed in HEK293 cells incubated for 1 hr by gamma counting analysis | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 4. | ALA3803376 | B | Displacement of 125I-NDP-MSH from mouse MC1R expressed in HEK293 cells incubated for 1 hr by gamma counting analysis relative to Ac-His-DPhe-Arg-Trp-NH2 | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA3803377 | B | Displacement of 125I-NDP-MSH from mouse MC3R expressed in HEK293 cells incubated for 1 hr by gamma counting analysis relative to Ac-His-DPhe-Arg-Trp-NH2 | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 6. | ALA3803378 | B | Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysis relative to Ac-His-DPhe-Arg-Trp-NH2 | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 7. | ALA3803379 | F | Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay | Mus musculus | 15 | cell-based format | Scientific Literature | ||
| 8. | ALA3803659 | F | Partial agonist activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation at 100 uM incubated for 2 hrs by alphascreen assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3803660 | F | Antagonist activity against mouse MC3R expressed in HEK293 cells assessed as NDP-MSH-stimulated cAMP accumulation incubated for 2 hrs by alphascreen assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3803661 | F | Agonist activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation at 100 uM incubated for 2 hrs by alphascreen assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA3803662 | F | Antagonist activity against mouse MC4R expressed in HEK293 cells assessed as NDP-MSH-stimulated cAMP accumulation incubated for 2 hrs by alphascreen assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA3803664 | F | Partial agonist activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation at 100 uM incubated for 2 hrs by alphascreen assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3803665 | F | Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assay relative to Ac-His-DNal(2')-Arg-Trp-NH2 | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4309182 | F | Agonist activity at human FLAG-tagged MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation at 10 uM after 2 hrs by AlphaScreen assay relative to NDP-MSH | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA4309183 | F | Antagonist activity at human FLAG-tagged MC4R expressed in HEK293 cells assessed as reduction in NDP-MSH-induced intracellular cAMP accumulation after 2 hrs by AlphaScreen assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA4309185 | B | Agonist activity at human FLAG-tagged MC4R expressed in HTLA cells assessed as induction of beta-arrestin recruitment at 10 uM after 18 hrs by Presto-tango assay relative to NDP-MSH | Homo sapiens | 9 | cell-based format | Scientific Literature |
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