# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3802287 | B | Inhibition of human recombinant GST-tagged ERK1 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured after 1 hr by Z-LYTE assay | Homo sapiens | 37 | ALA3797088 | assay format | Scientific Literature | |
2. | ALA3802288 | B | Inhibition of human recombinant GST-tagged ERK2 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured after 1 hr by Z-LYTE assay | Homo sapiens | 38 | ALA3797088 | assay format | Scientific Literature | |
3. | ALA3802289 | B | Inhibition of c-MET (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
4. | ALA3802290 | B | Inhibition of IGF1R (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
5. | ALA3802291 | B | Inhibition of ALK (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
6. | ALA3802292 | B | Inhibition of FLT1 (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
7. | ALA3802293 | B | Inhibition of ABL (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
8. | ALA3802294 | B | Inhibition of PDGFRbeta (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
9. | ALA3802295 | B | Inhibition of KDR (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
10. | ALA3802296 | B | Inhibition of RET (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
11. | ALA3802297 | B | Inhibition of EGFR (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
12. | ALA3802298 | B | Inhibition of ERBB2 (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
13. | ALA3802299 | B | Inhibition of c-Src (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
14. | ALA3802300 | B | Inhibition of EPHA2 (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
15. | ALA3802301 | B | Inhibition of FGFR1 (unknown origin) by Z-LYTE assay | Homo sapiens | 2 | ALA3797088 | single protein format | Scientific Literature | |
16. | ALA3802302 | F | Antiproliferative activity against human HT-29 cells harboring B-RAF V600E mutant after 72 hrs by SRB assay | Homo sapiens | 38 | ALA3797088 | cell-based format | Scientific Literature | |
17. | ALA3802303 | B | Inhibition of ERK1/ERK2 in human HT-29 cells assessed as reduction in p90RSK phosphorylation after 2 hrs by Western blot analysis | Homo sapiens | 3 | ALA3797088 | cell-based format | Scientific Literature | |
18. | ALA3802304 | B | Inhibition of ERK phosphorylation in human HT-29 cells after 2 hrs by Western blot analysis | Homo sapiens | 3 | ALA3797088 | cell-based format | Scientific Literature | |
19. | ALA3802306 | A | AUC (0 to 24 hrs) in mouse at 5 mg/kg, po | Mus musculus | 2 | ALA3797088 | organism-based format | Scientific Literature | |
20. | ALA3802308 | A | Oral bioavailability in mouse at 5 mg/kg | Mus musculus | 2 | ALA3797088 | organism-based format | Scientific Literature |