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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3801235 F Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubated for 1 hr followed CCL25 addition by FLIPR assay Homo sapiens 68 ALA3797083 cell-based format Scientific Literature 2. ALA3801236 F Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubated for 1 hr followed CCL25 addition by FLIPR assay Homo sapiens 14 ALA3797083 cell-based format Scientific Literature 3. ALA3801237 B Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCl25-mediated cell migration preincubated for 30 mins followed CCL25 addition incubated for 2 hrs by ChemoTx plate system Homo sapiens 14 ALA3797083 cell-based format Scientific Literature 4. ALA3801238 P Solubility of compound at pH 7.4 buffer 8 ALA3797083 small-molecule physicochemical format Scientific Literature 5. ALA3801239 A Metabolic stability of compound in human liver microsomes assessed as remaining compound at 37 deg C Homo sapiens 8 ALA3797083 tissue-based format Scientific Literature 6. ALA3801240 A Metabolic stability of compound in mouse liver microsomes assessed as remaining compound at 37 deg C Mus musculus 8 ALA3797083 tissue-based format Scientific Literature 7. ALA3801241 A Elimination half life in mouse at 1 mg/kg, iv Mus musculus 8 ALA3797083 organism-based format Scientific Literature 8. ALA3801242 A Clearance in mouse at 1 mg/kg, iv Mus musculus 8 ALA3797083 organism-based format Scientific Literature 9. ALA3801243 A AUC in mouse at 10 mg/kg, po Mus musculus 8 ALA3797083 organism-based format Scientific Literature 10. ALA3801244 A Absolute bioavailability in mouse at 1 mg/kg, iv 10 mg/kg, po Mus musculus 8 ALA3797083 organism-based format Scientific Literature 11. ALA3801433 F Anticolitis activity in DSS-induced acute colitis C57BL/6 mouse model assessed as reduction in disease activity index at 30 mg/kg, sc bid for 10 days Mus musculus 1 ALA3797083 organism-based format Scientific Literature 12. ALA3801434 F Anticolitis activity in DSS-induced acute colitis C57BL/6 mouse model assessed as reduction in disease activity index at 3 mg/kg, po bid for 10 days Mus musculus 3 ALA3797083 organism-based format Scientific Literature 13. ALA3801435 F Anticolitis activity in DSS-induced acute colitis C57BL/6 mouse model assessed as reduction in disease activity index at 10 mg/kg, po bid for 10 days Mus musculus 3 ALA3797083 organism-based format Scientific Literature 14. ALA3801436 F Anticolitis activity in DSS-induced acute colitis C57BL/6 mouse model assessed as reduction in disease activity index at 30 mg/kg, po bid for 10 days Mus musculus 3 ALA3797083 organism-based format Scientific Literature 15. ALA3801437 F Anticolitis activity in DSS-induced acute colitis C57BL/6 mouse model assessed as reduction in disease activity index at 100 mg/kg, po bid for 10 days Mus musculus 3 ALA3797083 organism-based format Scientific Literature 16. ALA3801438 F Anticolitis activity in DSS-induced chronic colitis C57BL/6 mouse model assessed as reduction in disease activity index at 30 mg/kg, po bid for 30 days Mus musculus 3 ALA3797083 organism-based format Scientific Literature