# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3801235 | F | Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubated for 1 hr followed CCL25 addition by FLIPR assay | Homo sapiens | 68 | ALA3797083 | cell-based format | Scientific Literature | |
2. | ALA3801236 | F | Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubated for 1 hr followed CCL25 addition by FLIPR assay | Homo sapiens | 14 | ALA3797083 | cell-based format | Scientific Literature | |
3. | ALA3801237 | B | Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCl25-mediated cell migration preincubated for 30 mins followed CCL25 addition incubated for 2 hrs by ChemoTx plate system | Homo sapiens | 14 | ALA3797083 | cell-based format | Scientific Literature | |
4. | ALA3801238 | P | Solubility of compound at pH 7.4 buffer | 8 | ALA3797083 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA3801239 | A | Metabolic stability of compound in human liver microsomes assessed as remaining compound at 37 deg C | Homo sapiens | 8 | ALA3797083 | tissue-based format | Scientific Literature | |
6. | ALA3801240 | A | Metabolic stability of compound in mouse liver microsomes assessed as remaining compound at 37 deg C | Mus musculus | 8 | ALA3797083 | tissue-based format | Scientific Literature | |
7. | ALA3801241 | A | Elimination half life in mouse at 1 mg/kg, iv | Mus musculus | 8 | ALA3797083 | organism-based format | Scientific Literature | |
8. | ALA3801242 | A | Clearance in mouse at 1 mg/kg, iv | Mus musculus | 8 | ALA3797083 | organism-based format | Scientific Literature | |
9. | ALA3801243 | A | AUC in mouse at 10 mg/kg, po | Mus musculus | 8 | ALA3797083 | organism-based format | Scientific Literature | |
10. | ALA3801244 | A | Absolute bioavailability in mouse at 1 mg/kg, iv 10 mg/kg, po | Mus musculus | 8 | ALA3797083 | organism-based format | Scientific Literature |