| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3802882 | B | Inhibition of PI3Kdelta in human JeKo1 cells assessed as inhibition of AKT phosphorylation at Ser-473 residue after 1 hr | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3802883 | B | Inhibition of human recombinant PI3Kalpha using PIP2 as substrate preincubated for 20 mins followed by substrate addition measured after 80 mins by luminescence assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 3. | ALA3802884 | B | Inhibition of human recombinant PI3Kbeta using PIP2 as substrate preincubated for 20 mins followed by substrate addition measured after 80 mins by luminescence assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 4. | ALA3802885 | B | Inhibition of human recombinant PI3Kgamma using PIP2 as substrate preincubated for 20 mins followed by substrate addition measured after 80 mins by luminescence assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 5. | ALA3802886 | B | Inhibition of human recombinant PI3Kdelta using PIP2 as substrate preincubated for 20 mins followed by substrate addition measured after 80 mins by luminescence assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 6. | ALA3802887 | B | Inhibition of PI3Kalpha mutant in human BT474 cells assessed as inhibition of AKT phosphorylation at Thr-308 residue after 2 hrs by ELISA | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 7. | ALA3802888 | B | Inhibition of PI3Kbeta in PTEN deficient human MDA-MB-468 cells assessed as inhibition of AKT phosphorylation at Ser-473 residue after 2 hrs by plate reader analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 8. | ALA3802890 | P | Lipophilicity, log D of compound at pH 7.4 | 16 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA3802891 | A | Intrinsic clearance in human hepatocytes assessed per million cells | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 10. | ALA3802892 | P | Solubility in pH 7.4 phosphate buffer using solid compound | 12 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA3802893 | A | Apparent permeability from apical to basolateral side in human Caco2 cells at 10 uM for 2 hrs by LC-MS/MS analysis | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA3802894 | A | AUC in hairy mouse at 30 umol/kg, po | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 13. | ALA3802895 | P | Aqueous solubility of crystalline compound in fasted simulated intestinal fluid | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA3802896 | P | Aqueous solubility of crystalline compound in pH 6.5 buffer | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 15. | ALA3802897 | B | Inhibition of human ERG | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3802898 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA3802899 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA3802900 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3802901 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA3802902 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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