#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3804042	F	Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay	Homo sapiens	26	ALA3797196	cell-based format	Scientific Literature
2.	ALA3804043	F	Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as potentiation of glutamate-induced calcium mobilization at 30 uM relative to (-)-PHCCC	Homo sapiens	26	ALA3797196	cell-based format	Scientific Literature
3.	ALA3801271	F	Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat at 1 mg/kg, po administered 60 mins after haloperidol-challenge measured after 30 mins	Rattus norvegicus	2	ALA3797196	organism-based format	Scientific Literature
4.	ALA3801272	F	Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat at 10 mg/kg, po administered 60 mins after haloperidol-challenge measured after 30 mins	Rattus norvegicus	1	ALA3797196	organism-based format	Scientific Literature
5.	ALA3887397	F	Receptor Activity Assay: The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in particular mGluR4 activity, by any suitable known methodology known in the art. For example, Chinese Hamster Ovary (CHO) cells transfected with human mGluR4 or HEK cells co-transfected with rat mGluR4 and the G-protein regulated Inwardly Rectifying Potassium channel (GIRK) were plated in clear bottom assay plates for assay in a Hamamatsu FDSS Fluorometric Plate Reader. The cells were loaded with either a Ca2+-sensitive fluorescent dye or the thallium responsive dye and the plates were washed and placed into a suitable kinetic plate reader. For human mGluR4 assays, a fluorescence baseline was established for 3-5 seconds, the disclosed compounds were then added to the cells, and the response in cells was measured.		90	ALA3886304	cell-based format	BindingDB Database
6.	ALA4233470	F	Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux preincubated for 2.5 mins followed by glutamate addition by Fluo-4-AM dye based fluorescence assay	Homo sapiens	47	ALA4229425	cell-based format	Scientific Literature
7.	ALA4233472	A	Clearance in rat liver microsomes	Rattus norvegicus	8	ALA4229425	microsome format	Scientific Literature
8.	ALA4233473	A	Fraction unbound in human plasma	Homo sapiens	8	ALA4229425	cell-free format	Scientific Literature
9.	ALA4233474	A	Fraction unbound in rat plasma	Rattus norvegicus	8	ALA4229425	cell-free format	Scientific Literature
10.	ALA4233475	A	Inhibition of CYP1A2 in human liver microsomes	Homo sapiens	8	ALA4229425	microsome format	Scientific Literature
11.	ALA4233476	A	Activation of human AhR assessed as induction of CYP1A2 relative to control	Homo sapiens	8	ALA4229425	single protein format	Scientific Literature
12.	ALA4310058	F	Reversal of haloperidol-induced catalepsy in Sprague-Dawley rat assessed as decrease in latency to remove forepaws from bar at 10 mg/kg, po administered 30 mins prior to test	Rattus norvegicus	3	ALA4308847	organism-based format	Scientific Literature
13.	ALA4737566	F	Reversal of haloperidol-induced catalepsy in ip dosed Sprague-Dawley rat assessed as reduction in catalepsy measured after 15 mins relative to untreated control	Rattus norvegicus	1	ALA4732192	organism-based format	Scientific Literature
14.	ALA4737567	F	Reversal of haloperidol-induced catalepsy in ip dosed Sprague-Dawley rat assessed as latency time for withdrawl measured after 15 mins (Rvb = 49.8 sec)	Rattus norvegicus	1	ALA4732192	organism-based format	Scientific Literature
15.	ALA5128636	F	Agonist activity at human mGlu4 receptor assessed as increase in calcium flux	Homo sapiens	1	ALA5126552	assay format	Scientific Literature
16.	ALA5128637	B	Agonist activity at rat mGlu4 receptor assessed as increase in calcium flux	Rattus norvegicus	1	ALA5126552	assay format	Scientific Literature
17.	ALA5128638	A	Oral bioavailability in 6-OHDA-unilateral lesioned rat model of Parkinson's disease at 15 mg/kg	Rattus norvegicus	1	ALA5126552	organism-based format	Scientific Literature