# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3807062 | B | Displacement of 33-P-S1P from from human S1P receptor expressed in CHO cell membranes after 50 mins by scintillation counting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA3807063 | F | Agonist activity at human S1P1 receptor expressed in CHO cells assessed as cAMP accumulation after 30 mins by HTRF analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA3807064 | B | Agonist activity at human S1P1 receptor expressed in CHO cells assessed as ERK phosphorylation after 7 mins by alphaLISA | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA3807065 | B | Agonist activity at human S1P1 receptor expressed in CHO cells co-expressing GFP assessed as cellular internalization after 45 mins by Hoechst assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA3807066 | F | Agonist activity at human S1P1 receptor by GTPgammaS binding assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
6. | ALA3807067 | F | Antagonist activity at human S1P3 receptor by GTPgammaS binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA3807068 | F | Agonist activity at human S1P3 receptor by GTPgammaS binding assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA3807069 | F | Agonist activity at human S1P4 receptor by GTPgammaS binding assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA3807070 | F | Agonist activity at human S1P5 receptor by GTPgammaS binding assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA3807071 | A | Cmax in mouse at 1 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
11. | ALA3807072 | A | Tmax in mouse at 1 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
12. | ALA3807073 | A | AUClast in mouse at 1 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
13. | ALA3807074 | A | AUC in mouse at 1 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
14. | ALA3807075 | A | Half life in mouse at 0.5 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA3807076 | A | MRT in mouse at 0.5 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA3807359 | T | Toxicity in guinea pig heart assessed as reduction in ventricular rate at 100 nM after 10 mins by ECG analysis | Cavia porcellus | 2 | tissue-based format | Scientific Literature | ||
17. | ALA3807361 | T | Toxicity in guinea pig heart assessed as third degree AV block at 100 nM after 10 mins by ECG analysis | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
18. | ALA3807362 | T | Toxicity in guinea pig heart assessed as reduction in ventricular rate at 1000 nM after 10 mins by ECG analysis | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
19. | ALA3807363 | T | Toxicity in guinea pig heart assessed as third degree AV block at 1000 nM after 10 mins by ECG analysis | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
20. | ALA3807366 | T | Toxicity in human-inducible pluripotent stem cell-derived Cardiomyocyte assessed as reduction in cardiomyocyte beating at 1 nM after 2 hrs | Homo sapiens | 2 | assay format | Scientific Literature |