# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3807261 | B | Inhibition of recombinant Influenza A/X-31 virus PA (N-terminal amino acid residue 1-217) transfected in Escherichia coli assessed as endonucleolytic digestion using single-stranded circular DNA plasmid M13mp18 after 2 hrs by ethidium bromide staining based agarose gel electrophoresis | Influenza A virus (A/X-31(H3N2)) | 7 | assay format | Scientific Literature | ||
2. | ALA3807262 | A | Cytotoxicity against HEK293T cells assessed as effect on cell morphology after 24 hrs by microscopic analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA3807263 | B | Inhibition of recombinant Influenza A/X-31 virus PA infected in HEK293T cells after 2 hrs by vRNP reconstitution assay | Influenza A virus (A/X-31(H3N2)) | 7 | cell-based format | Scientific Literature | ||
4. | ALA3807265 | A | Cytotoxicity against human Huh5-2 cells assessed as cell viability after 72 hrs by Alamar blue dye based colorimetric analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA3807266 | F | Antiviral activity against HCV Con1 infected in human Huh5-2 cells haboring firefly luciferase expressing subgenomic replicon of HCV genotype 1b after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 7 | organism-based format | Scientific Literature | ||
6. | ALA3807267 | U | Selectivity index, ratio of LC50 for human Huh5-2 cells to EC50 for HCV Con1 infected in human Huh5-2 cells haboring firefly luciferase expressing subgenomic replicon of HCV genotype 1b | 3 | cell-based format | Scientific Literature | |||
7. | ALA3807269 | P | Dissociation constant, pKa of compound | 7 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA3807270 | P | Lipophilicity, log D of compound | 7 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA4374341 | F | Antiviral activity against HCV genotype 1b Con1 infected in human HuH5.2 cells assessed as reduction in viral replication incubated for 3 days by luciferase reporter gene assay | Hepacivirus hominis | 11 | organism-based format | Scientific Literature | ||
10. | ALA4374345 | A | Cytotoxicity against human HuH5.2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
11. | ALA4374346 | T | Selectivity index, ratio of CC50 for human Huh5.2 cells to EC50 for HCV genotype 1b Con1 | 10 | assay format | Scientific Literature |