# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3807261 | Binding | Inhibition of recombinant Influenza A/X-31 virus PA (N-terminal amino acid residue 1-217) transfected in Escherichia coli assessed as endonucleolytic digestion using single-stranded circular DNA plasmid M13mp18 after 2 hrs by ethidium bromide staining based agarose gel electrophoresis | Influenza A virus (A/X-31(H3N2)) | 7 | ALA3804762 | assay format | Scientific Literature | |
2. | ALA3807262 | ADME | Cytotoxicity against HEK293T cells assessed as effect on cell morphology after 24 hrs by microscopic analysis | Homo sapiens | 7 | ALA3804762 | cell-based format | Scientific Literature | |
3. | ALA3807263 | Binding | Inhibition of recombinant Influenza A/X-31 virus PA infected in HEK293T cells after 2 hrs by vRNP reconstitution assay | Influenza A virus (A/X-31(H3N2)) | 7 | ALA3804762 | cell-based format | Scientific Literature | |
4. | ALA3807265 | ADME | Cytotoxicity against human Huh5-2 cells assessed as cell viability after 72 hrs by Alamar blue dye based colorimetric analysis | Homo sapiens | 7 | ALA3804762 | cell-based format | Scientific Literature | |
5. | ALA3807266 | Functional | Antiviral activity against HCV Con1 infected in human Huh5-2 cells haboring firefly luciferase expressing subgenomic replicon of HCV genotype 1b after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 7 | ALA3804762 | organism-based format | Scientific Literature | |
6. | ALA3807267 | Unassigned | Selectivity index, ratio of LC50 for human Huh5-2 cells to EC50 for HCV Con1 infected in human Huh5-2 cells haboring firefly luciferase expressing subgenomic replicon of HCV genotype 1b | 3 | ALA3804762 | cell-based format | Scientific Literature | ||
7. | ALA3807269 | Physicochemical | Dissociation constant, pKa of compound | 7 | ALA3804762 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA3807270 | Physicochemical | Lipophilicity, log D of compound | 7 | ALA3804762 | small-molecule physicochemical format | Scientific Literature |