| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3807033 | B | Inhibition of His-tagged human HK1 (11 to 917 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo assay in presence of MgATP | Homo sapiens | 25 | ALA3804808 | assay format | Scientific Literature | |
| 2. | ALA3807034 | B | Inhibition of His-tagged human HK2 (17 to 916 residues) expressed in Escherichia coli BL21(DE3) using glucose as substrate after 45 mins by ADP-glo assay in presence of MgATP | Homo sapiens | 25 | ALA3804808 | assay format | Scientific Literature | |
| 3. | ALA3807036 | B | Inhibition of HK2 in human UM-UC-3 cells using 2FDG as substrate assessed as suppression of G6P production preincubated for 30 mins followed by substrate treatment for 90 mins by resazurin assay | Homo sapiens | 3 | ALA3804808 | cell-based format | Scientific Literature | |
| 4. | ALA3807037 | B | Inhibition of HK2 in human UM-UC-3 cells assessed as reduction in glucose consumption incubated up to 20 hrs | Homo sapiens | 1 | ALA3804808 | cell-based format | Scientific Literature | |
| 5. | ALA3807038 | B | Inhibition of HK2 in human UM-UC-3 cells assessed as production of [3-13C]-lactate from D-[1,6-13C2]glucose at 10 uM preincubated for 1 hr followed by D-[1,6-13C2]glucose addition measured every 10 mins by real-time 13C-NMR spectroscopic analysis | Homo sapiens | 1 | ALA3804808 | cell-based format | Scientific Literature | |
| 6. | ALA3807041 | B | Inhibition of HK4 (unknown origin) | Homo sapiens | 1 | ALA3804808 | single protein format | Scientific Literature | |
| 7. | ALA3807227 | B | Selectivity ratio of IC50 for HK4 (unknown origin) to IC50 for His-tagged human HK2 (17 to 916 residues) | Homo sapiens | 1 | ALA3804808 | assay format | Scientific Literature |
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