# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3811932 | F | Antimalarial activity against Plasmodium falciparum 3D7 infected human erythrocytes assessed as parasite growth inhibition after 72 hrs by spectrophotometry | Plasmodium falciparum | 22 | organism-based format | Scientific Literature | ||
2. | ALA3811933 | B | Inhibition of class 1 histone deacetylase in human HeLa cells using FLUOR DE LYS as fluorescent substrate after 4 hrs by spectrophotometry | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA3811934 | B | Inhibition of recombinant human His-tagged HDAC1 expressed in insect cells preincubated for 10 mins followed by addition of FLUOR DE LYS as fluorescent substrate measured after 1 hr by spectrophotometry | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
4. | ALA3811935 | T | Selectivity index, ratio of IC50 for HDAC1 in human HeLa cells to EC50 for Plasmodium falciparum 3D7 infected human erythrocytes | 22 | cell-based format | Scientific Literature | |||
5. | ALA5248041 | B | Selectivity ratio of IC50 for human recombinant his tagged HDAC1 to IC50 for human recombinant his tagged HDAC3 | Homo sapiens | 8 | assay format | Scientific Literature | ||
6. | ALA5248042 | B | Inhibition of human recombinant his tagged HDAC3 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis | Homo sapiens | 8 | assay format | Scientific Literature | ||
7. | ALA5248044 | B | Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis | Homo sapiens | 20 | assay format | Scientific Literature |