# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3810641 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
2. | ALA3810642 | F | Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA3810643 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTS assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA3810644 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA3810645 | B | Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate at 25 uM after 30 mins relative to control | Homo sapiens | 20 | single protein format | Scientific Literature | ||
6. | ALA3810646 | B | Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA3810810 | A | Cytotoxicity against MDCK cells after 36 hrs | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
8. | ALA4186600 | F | Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 1 hr after test compound dosing measured for 3 mins relative to control | Mus musculus | 11 | organism-based format | Scientific Literature | ||
9. | ALA4186601 | F | Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 2.5 hrs after test compound dosing measured for 3 mins relative to control | Mus musculus | 12 | organism-based format | Scientific Literature | ||
10. | ALA4186602 | F | Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 5 hrs after test compound dosing measured for 3 mins relative to control | Mus musculus | 12 | organism-based format | Scientific Literature | ||
11. | ALA4186609 | F | Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 20 mg/kg, po treated with ammonia 1 hr before and 1 hr after test compound dosing measured for 3 mins | Mus musculus | 9 | organism-based format | Scientific Literature | ||
12. | ALA4186610 | F | Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 20 mg/kg, po treated with ammonia 1 hr before and 2.5 hrs after test compound dosing measured for 3 mins | Mus musculus | 9 | organism-based format | Scientific Literature | ||
13. | ALA4186611 | F | Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 20 mg/kg, po treated with ammonia 1 hr before and 5 hrs after test compound dosing measured for 3 mins | Mus musculus | 9 | organism-based format | Scientific Literature | ||
14. | ALA4612141 | B | Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 mins | Homo sapiens | 19 | assay format | Scientific Literature | ||
15. | ALA4817459 | F | Anti-austerity activity against human PANC-1 cells assessed as cell killing in nutrient deprived medium | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
16. | ALA4817460 | F | Anti-austerity activity against human MIA PaCa-2 cells assessed as cell killing in nutrient deprived medium | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
17. | ALA4817461 | F | Anti-austerity activity against human PSN1 cells assessed as cell killing in nutrient deprived medium | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
18. | ALA4817462 | F | Anti-austerity activity against human KLM-1 cells assessed as cell killing in nutrient deprived medium | Homo sapiens | 5 | cell-based format | Scientific Literature |