#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3816161	ADME	Oral bioavailability in Sprague-Dawley rat at 5 mg/kg	Rattus norvegicus	1	ALA3813614	organism-based format	Scientific Literature
2.	ALA3816162	ADME	Plasma protein binding in CD1 mouse at 25 mg/kg, po	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
3.	ALA3816163	ADME	AUC in Sprague-Dawley rat at 5 mg/kg, po	Rattus norvegicus	1	ALA3813614	organism-based format	Scientific Literature
4.	ALA3816164	ADME	Drug level in CD1 mouse brain at 25 mg/kg, po administered as single dose measured at 1 hr post dose by LC-MS/MS analysis	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
5.	ALA3816165	Toxicity	Toxicity in nude NCR mouse xenografted with PTEN null human U87MG/M cells assessed as change in body weight at 2.2 to 17.9 mg/kg, po qd administered through gavage for 23 days	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
6.	ALA3816166	Binding	Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as substrate incubated for 30 mins in presence of TAMRA-PIP3 by fluorescence polarization assay	Homo sapiens	11	ALA3813614	single protein format	Scientific Literature
7.	ALA3816167	Binding	Inhibition of human recombinant mTOR (1360 to 2549 residues) expressed in insect cells assessed as inhibition of GFP-labeled 4-EBP1 phosphorylation at Thr-37/46 residues incubated for 30 mins by FRET assay	Homo sapiens	6	ALA3813614	cell-based format	Scientific Literature
8.	ALA3816168	Functional	Antiproliferative activity against human PC3 cells after 3 days by CellTitre-Glo assay	Homo sapiens	11	ALA3813614	cell-based format	Scientific Literature
9.	ALA3816169	ADME	Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in MDCK1 cells expressing human MDR1 at 5 uM incubated for 2 hrs by LC-MS/MS analysis	Canis lupus familiaris	10	ALA3813614	cell-based format	Scientific Literature
10.	ALA3816170	ADME	Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in MDCK2 cells expressing mouse BCRP1 at 5 uM incubated for 2 hrs by LC-MS/MS analysis	Canis lupus familiaris	11	ALA3813614	cell-based format	Scientific Literature
11.	ALA3816174	Binding	Inhibition of recombinant human His-tagged cytoplasmic AXL (473 nd residues) expressed in insect cells at 1 uM relative to control	Homo sapiens	1	ALA3813614	cell-based format	Scientific Literature
12.	ALA3816175	ADME	Clearance in CD1 mouse at 1 mg/kg, iv	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
13.	ALA3816176	ADME	Volume of distribution at steady state in CD1 mouse at 1 mg/kg, iv	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
14.	ALA3816177	ADME	Clearance in Sprague-Dawley rat at 1 mg/kg, iv	Rattus norvegicus	1	ALA3813614	organism-based format	Scientific Literature
15.	ALA3816178	ADME	Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv	Rattus norvegicus	1	ALA3813614	organism-based format	Scientific Literature
16.	ALA3816179	ADME	AUC in CD1 mouse at 25 mg/kg, po	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
17.	ALA3816180	ADME	Oral bioavailability in CD1 mouse at 25 mg/kg	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
18.	ALA3816181	ADME	Plasma protein binding in Sprague-Dawley rat at 5 mg/kg, po	Rattus norvegicus	1	ALA3813614	organism-based format	Scientific Literature
19.	ALA3816984	ADME	Ratio of drug level in CD1 mouse brain to plasma at 25 mg/kg, po after 1 to 6 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature
20.	ALA3816985	ADME	Ratio of unbound fraction in CD1 mouse brain to plasma at 25 mg/kg, po after 1 to 6 hrs by LC-MS/MS analysis	Mus musculus	1	ALA3813614	organism-based format	Scientific Literature