# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3817137 | Binding | Inhibition of EGFR T790M/L858R double mutant autophosphorylation in human NCI-H1975 cells incubated for 2 hrs by ELISA | Homo sapiens | 24 | ALA3813644 | cell-based format | Scientific Literature | |
2. | ALA3817138 | Binding | Inhibition of EGFR exon19 deletion activating mutant autophosphorylation in human PC9 cells incubated for 2 hrs by ELISA | Homo sapiens | 22 | ALA3813644 | cell-based format | Scientific Literature | |
3. | ALA3817139 | Binding | Inhibition of wild-type EGFR autophosphorylation in human LoVo cells incubated for 2 hrs followed by EGF-stiumlation for 10 mins by ELISA | Homo sapiens | 22 | ALA3813644 | cell-based format | Scientific Literature | |
4. | ALA3817140 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 12 | ALA3813644 | tissue-based format | Scientific Literature | |
5. | ALA3817141 | Physicochemical | Solubility of compound at pH 7.4 | 16 | ALA3813644 | small-molecule physicochemical format | Scientific Literature |