| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3821098 | F | Increase in intracellular ROS accumulation in human U2OS/DX30 cells at 5 uM incubated for 24 hrs in presence of hydroxocobalamin by DCFDA-AM probe-based fluorimetrical analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3821099 | F | Increase in intracellular ROS accumulation in human U2OS/DX580 cells at 5 uM incubated for 24 hrs in presence of hydroxocobalamin by DCFDA-AM probe-based fluorimetrical analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA3821100 | B | Inhibition of human topoisomerase 2-mediated DNA cleavage at 5 uM using supercoiled pHOT1 plasmid as substrate by agarose gel electrophoresis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 4. | ALA3821103 | P | Stability of compound in pre-heated IMDM at 200 uM at 37 degC by RP-HPLC analysis | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA3821104 | P | Induction of H2S release from compound in IMDM at 100 uM incubated for 1 to 24 hrs using DNS-Az by fluorimetric assay-based HPLC analysis | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA3822110 | P | Half life of compound in pre-heated DMEM at 200 uM at 37 degC by RP-HPLC analysis | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA3822111 | A | Half life of compound assessed as human serum esterase-mediated degradation at 100 uM by RP-HPLC analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 8. | ALA3822112 | P | Induction of H2S release from compound in DMEM at 100 uM incubated for 1 to 24 hrs using DNS-Az by fluorimetric assay-based HPLC analysis | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA3822113 | F | Induction of H2S release from compound in human serum at 100 uM incubated for 1 to 24 hrs using DNS-Az by fluorimetric assay-based HPLC analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 10. | ALA3822114 | A | Drug uptake in rat H9c2 cells at 5 uM incubated for 24 hrs by fluorimetrical analysis | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA3822115 | A | Cytotoxicity in rat H9c2 cells at 5 uM incubated for 24 hrs by LDH release-based spectrofluorimetrical analysis relative to control | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA3822118 | A | Drug uptake in human U2OS cells at 5 uM incubated for 24 hrs by fluorimetrical analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA3822119 | A | Drug uptake in human U2OS/DX30 cells at 5 uM incubated for 24 hrs by fluorimetrical analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA3822120 | A | Drug uptake in human U2OS/DX100 cells at 5 uM incubated for 24 hrs by fluorimetrical analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA3822121 | A | Drug uptake in human U2OS/DX580 cells at 5 uM incubated for 24 hrs by fluorimetrical analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA3822246 | A | Cytotoxicity in rat H9c2 cells assessed as intracellular ROS accumulation at 5 uM incubated for 24 hrs by DCFDA-AM probe-based fluorimetrical analysis relative to control | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
| 17. | ALA3822247 | A | Cytotoxicity in rat H9c2 cells assessed as intracellular ROS accumulation at 5 uM incubated for 24 hrs in presence of hydroxocobalamin by DCFDA-AM probe-based fluorimetrical analysis relative to control | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
| 18. | ALA3822253 | A | Cytotoxicity in rat H9c2 cells at 5 uM incubated for 24 hrs in presence of NAC by LDH release-based spectrofluorimetrical analysis relative to control | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 19. | ALA3822255 | F | Induction of intracellular ROS accumulation in human U2OS cells at 5 uM incubated for 24 hrs by DCFDA-AM probe-based fluorimetrical analysis relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 20. | ALA3822256 | F | Induction of intracellular ROS accumulation in human U2OS/DX100 cells at 5 uM incubated for 24 hrs by DCFDA-AM probe-based fluorimetrical analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |
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