# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3821389 | B | Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate assay in presence of SAM | Homo sapiens | 6 | assay format | Scientific Literature | ||
2. | ALA3821390 | B | Binding affinity to COMT in human HepG2 assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of active Tcp-CC-13 by differential competition capture compound mass spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
3. | ALA3821391 | A | Binding affinity to ADL1 in human HepG2 assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of active Tcp-CC-13 by differential competition capture compound mass spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
4. | ALA3821392 | A | Binding affinity to CCBL2 in human HepG2 assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of active Tcp-CC-13 by differential competition capture compound mass spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA3821393 | A | Binding affinity to GCDH in human HepG2 assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of active Tcp-CC-13 by differential competition capture compound mass spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA3821394 | A | Binding affinity to PDXK in human HepG2 assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of inactive Tcp-CC 14 by differential competition capture compound mass spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
7. | ALA3821395 | A | Binding affinity to AKR1B10 in human HepG2 assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of inactive Tcp-CC 14 by differential competition capture compound mass spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
8. | ALA3821396 | A | Binding affinity to NIPSNAP3A in human HepG2 assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of inactive Tcp-CC 14 by differential competition capture compound mass spectrometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
9. | ALA3821398 | B | Binding affinity to human recombinant HIBCH assessed as intensity fold change of cumulated normalized intensity of protein between capture and competition assay at 100 uM after 1 hr in presence of active Tcp-CC-13 by differential competition capture compound mass spectrometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
10. | ALA3821400 | A | Binding affinity to human recombinant HIBCH after 1 hr in presence of active Tcp-CC-13 by Western blot analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
11. | ALA3821401 | B | Binding affinity to His-tagged human recombinant soluble COMT after 1 hr in presence of active Tcp-CC-13 by Western blot analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
12. | ALA3821402 | B | Binding affinity to His-tagged human recombinant soluble COMT after 1 hr in presence of active Tcp-CC-13 by streptavidin based Western blot analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
13. | ALA3821403 | T | Mitochondrial toxicity in human HepG2 cells assessed as ratio of ATP generation in presence of glucose media to galactose media up to 1000 uM after 2 mins by mitochondria ToxGlo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA3821404 | T | Mitochondrial toxicity in human HepG2 cells assessed as mitochondrial membrane potential levels at 50 uM by TMRE-based mitochondria membrane potential assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA3821405 | T | Mitochondrial toxicity in human HepG2 cells assessed as mitochondrial membrane potential levels at 100 uM by TMRE-based mitochondria membrane potential assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature |