#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3822175	Unassigned	Ratio of fCmax associated with acute adverse effect in mouse at 12.5 to 25 mg/kg, po to IC50 for PAK1/2-mediated phosphorylation of MEK1 at serine 298 in human EBC1 cells		1	ALA3817726	organism-based format	Scientific Literature
2.	ALA3822287	ADME	Plasma concentration in mouse at 25 mg/kg, po at 15 mins	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
3.	ALA3822288	Toxicity	Toxicity in mouse assessed as mortality at 25 mg/kg, po after 2 hrs	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
4.	ALA3822289	Toxicity	Toxicity in mouse assessed as mortality at 12.5 mg/kg, po after 0.25 hrs	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
5.	ALA3822290	Toxicity	Toxicity in mouse assessed as mortality at 12.5 mg/kg, po after 0.5 hrs	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
6.	ALA3822291	ADME	Plasma concentration in mouse at 12.5 mg/kg, po at 0.25 hrs	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
7.	ALA3822292	ADME	Plasma concentration in mouse at 12.5 mg/kg, po at 0.5 hrs	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
8.	ALA3822293	ADME	Fraction unbound in mouse plasma at 25 mg/kg, po at 0.25 hrs	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
9.	ALA3820948	Binding	Inhibition of human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) expressed in Escherichia coli BL21(DE3) assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins followed by ATP addition measured after 60 mins by Z'-LYTE assay	Homo sapiens	26	ALA3817726	assay format	Scientific Literature
10.	ALA3820950	Binding	Selectivity for human recombinant N-terminal 6-His-tagged PAK1 kinase domain (249 to 545 residues) over LCK (unknown origin)	Homo sapiens	18	ALA3817726	assay format	Scientific Literature
11.	ALA3820951	Binding	Inhibition of PAK1/2 in human EBC1 cells assessed as phosphorylation of MEK1 at serine 298 after 2 hrs by HTRF assay	Homo sapiens	18	ALA3817726	cell-based format	Scientific Literature
12.	ALA3820952	Physicochemical	Lipophilicity, log D of the compound at pH 7.4		10	ALA3817726	small-molecule physicochemical format	Scientific Literature
13.	ALA3820953	Physicochemical	Kinetic solubility of the compound at pH 7.4		10	ALA3817726	small-molecule physicochemical format	Scientific Literature
14.	ALA3820954	ADME	Apparent permeability across apical to basolateral side in MDCK cells at 10 uM after 60 mins	Canis lupus familiaris	10	ALA3817726	cell-based format	Scientific Literature
15.	ALA3820956	ADME	Efflux ratio of permeability across basolateral to apical side over apical to basolateral side in MDCK cells at 10 uM after 60 mins	Canis lupus familiaris	10	ALA3817726	cell-based format	Scientific Literature
16.	ALA3820957	Binding	Inhibition of human recombinant PAK2 assessed as phosphorylation of coumarin labeled FRET peptide substrate at Ser/Thr19 preincubated for 10 mins followed by ATP addition measured after 60 mins by Z'-LYTE assay	Homo sapiens	10	ALA3817726	single protein format	Scientific Literature
17.	ALA3820958	ADME	Fraction unbound in mouse plasma at 12.5 to 25 mg/kg, po	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
18.	ALA3820967	ADME	Cmax associated with acute adverse effect in mouse at 12.5 to 25 mg/kg, po	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature
19.	ALA3821131	ADME	fCmax associated with acute adverse effect in mouse at 12.5 to 25 mg/kg, po	Mus musculus	1	ALA3817726	organism-based format	Scientific Literature