# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3819878 | ADME | Cytotoxicity against human Ca9-22 cells assessed as cell survival at 5 uM preincubated for 4 hrs followed by 1 Jcm'-2 UVA irradiation measured after 24 hrs by MTT assay relative to control | Homo sapiens | 16 | ALA3817730 | cell-based format | Scientific Literature | |
2. | ALA3819879 | ADME | Cytotoxicity against human Ca9-22 cells assessed as inhibition of cell survival at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 24 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA3817730 | cell-based format | Scientific Literature | |
3. | ALA3819880 | Functional | Anti-metastatic activity against human Ca9-22 cells assessed as inhibition of cell migration at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 16 hrs by wound healing assay relative to control | Homo sapiens | 6 | ALA3817730 | cell-based format | Scientific Literature | |
4. | ALA3819881 | Functional | Antiinvasive activity against human Ca9-22 cells assessed as cell invasion at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 22 hrs by boyden chamber assay relative to control | Homo sapiens | 6 | ALA3817730 | cell-based format | Scientific Literature | |
5. | ALA3819882 | Functional | Anti-metastatic activity against human Ca9-22 cells assessed as increase in syndecan-1 mRNA expression at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 8 hrs by qRT-PCR method | Homo sapiens | 1 | ALA3817730 | cell-based format | Scientific Literature | |
6. | ALA3819883 | Functional | Anti-metastatic activity against human Ca9-22 cells assessed as increase in TIMP3 mRNA expression at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 8 hrs by qRT-PCR method | Homo sapiens | 1 | ALA3817730 | cell-based format | Scientific Literature | |
7. | ALA3819884 | Functional | Anti-metastatic activity against human Ca9-22 cells assessed as reduction in heparanase mRNA expression at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 8 hrs by qRT-PCR method | Homo sapiens | 1 | ALA3817730 | cell-based format | Scientific Literature | |
8. | ALA3820043 | Binding | Inhibition of EGFR/ERK signalling in human Ca9-22 cells assessed as reduction in MMP2 mRNA expression at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 8 hrs by qRT-PCR method | Homo sapiens | 1 | ALA3817730 | cell-based format | Scientific Literature | |
9. | ALA3820146 | Binding | Inhibition of EGFR/ERK signalling in human Ca9-22 cells assessed as reduction in MMP9 mRNA expression at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation measured after 8 hrs by qRT-PCR method | Homo sapiens | 1 | ALA3817730 | cell-based format | Scientific Literature | |
10. | ALA3820147 | Binding | Inhibition of phosphorylated EGFR level in human Ca9-22 cells at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation by Western blot analysis | Homo sapiens | 3 | ALA3817730 | cell-based format | Scientific Literature | |
11. | ALA3820148 | Binding | Inhibition of phosphorylated ERK level in human Ca9-22 cells at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation by Western blot analysis | Homo sapiens | 3 | ALA3817730 | cell-based format | Scientific Literature | |
12. | ALA3820149 | Binding | Inhibition of EGFR/ERK signalling in human Ca9-22 cells assessed as reduction in MMP2 expression at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation by Western blot analysis | Homo sapiens | 3 | ALA3817730 | cell-based format | Scientific Literature | |
13. | ALA3820150 | Binding | Inhibition of EGFR/ERK signalling in human Ca9-22 cells assessed as reduction in MMP9 expression at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation by Western blot analysis | Homo sapiens | 3 | ALA3817730 | cell-based format | Scientific Literature | |
14. | ALA3820151 | Functional | Increase in TIMP3 expression in human Ca9-22 cells at 2 uM preincubated for 2 hrs followed by 0.5 Jcm'-2 UVA irradiation by Western blot analysis | Homo sapiens | 3 | ALA3817730 | cell-based format | Scientific Literature |