# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3821460 | B | Inhibition of human Akt1 PH domain using AKTide-2T as substrate at 100 uM by ELISA | Homo sapiens | 12 | ALA3817785 | single protein format | Scientific Literature | |
2. | ALA3821462 | B | Inhibition of N-terminal his-tagged full length human recombinant BTK PH domain expressed in baculovirus infected Sf9 insect cells at 100 uM by ADP-glo luminescence assay | Homo sapiens | 3 | ALA3817785 | cell-based format | Scientific Literature | |
3. | ALA3821465 | F | Antiproliferative activity against human TPC1 cells harboring RET/PTC-1 rearrangement assessed as cell growth inhibition after 72 hrs by coulter counter method | Homo sapiens | 4 | ALA3817785 | cell-based format | Scientific Literature | |
4. | ALA3821468 | F | Antiproliferative activity against human K1 cells expressing BRAF V600E/PI3K E542K mutants assessed as cell growth inhibition after 72 hrs by coulter counter method | Homo sapiens | 4 | ALA3817785 | cell-based format | Scientific Literature | |
5. | ALA3821469 | F | Antiproliferative activity against PTEN-deficient human Nim1 cells expressing BRAF V600E mutant assessed as cell growth inhibition after 72 hrs by coulter counter method | Homo sapiens | 4 | ALA3817785 | assay format | Scientific Literature | |
6. | ALA3821471 | F | Antiproliferative activity against human IGROV1 cells assessed as cell growth inhibition after 24 hrs by coulter counter method | Homo sapiens | 4 | ALA3817785 | cell-based format | Scientific Literature | |
7. | ALA3821626 | B | Inhibition of Akt in human IGROV1 cells assessed as reduction in GSK3alpha phosphorylation at Ser21 at 3 to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3817785 | cell-based format | Scientific Literature | |
8. | ALA3821627 | B | Inhibition of Akt in human IGROV1 cells assessed as reduction in GSK3beta phosphorylation at Ser9 at 3 to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3817785 | cell-based format | Scientific Literature | |
9. | ALA3821628 | B | Inhibition of Akt in human IGROV1 cells assessed as reduction in BAD phosphorylation at Ser136 at 3 to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3817785 | cell-based format | Scientific Literature |