#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3821483	Binding	Binding affinity to human recombinant FGF2 at 8 to 150 uM treated for 4 mins measured after 10 mins by surface plasmon resonance spectroscopic analysis	Homo sapiens	1	ALA3817782	single protein format	Scientific Literature
2.	ALA3821484	Physicochemical	Kinetic solubility in 3% DMSO solution in PBS up to 30 uM stirred for 5 mins by HPLC-MS/MS analysis		2	ALA3817782	small-molecule physicochemical format	Scientific Literature
3.	ALA3821486	Binding	Inhibition of human recombinant FGF2 assessed as reduction in HSPG/FGF2/FGDR interaction by measuring FGF2 mediated A475-CHO-flg-1A-luc cell to CHO-K1 cell adhesion at 100 uM incubated for 2 hrs by luciferase assay	Homo sapiens	1	ALA3817782	cell-based format	Scientific Literature
4.	ALA3821488	Binding	Inhibition of human recombinant FGF2 assessed as suppression of FGFR1 phosphorylation in mouse LLC cells at 100 uM incubated for 20 mins by Western blot analysis	Homo sapiens	1	ALA3817782	cell-based format	Scientific Literature
5.	ALA3821491	Functional	Antiproliferative activity against mouse LLC cells at 0.3 to 10 uM incubated for 48 hrs by PI-staining based flow cytometry	Mus musculus	1	ALA3817782	cell-based format	Scientific Literature
6.	ALA3821492	Functional	Antiproliferative activity against human NCI-H520 cells at 0.3 to 10 uM incubated for 72 hrs by PI-staining based flow cytometry	Homo sapiens	1	ALA3817782	cell-based format	Scientific Literature
7.	ALA3821493	Physicochemical	Kinetic solubility in DMEM buffer/1% DMSO assessed as recovered drug level at 10 uM after 4 hrs by HPLC-MS/MS analysis		2	ALA3817782	small-molecule physicochemical format	Scientific Literature
8.	ALA3821494	Physicochemical	Dissociation constant, pKa of the compound in methanol-water mixture at 25 +/- 1 degC by potentiometric pH-metric method		2	ALA3817782	small-molecule physicochemical format	Scientific Literature
9.	ALA3821495	Physicochemical	Kinetic solubility in DMEM buffer at 10 uM after 4 hrs in presence of EDTA by HPLC-MS/MS analysis		1	ALA3817782	small-molecule physicochemical format	Scientific Literature
10.	ALA3821496	Physicochemical	Kinetic solubility in DMEM buffer/1% DMSO assessed as recovered drug level at 6 uM after 4 hrs by HPLC-MS/MS analysis		1	ALA3817782	small-molecule physicochemical format	Scientific Literature
11.	ALA3821497	Physicochemical	Kinetic solubility in DMEM buffer/1% DMSO assessed as recovered drug level at 3 uM after 4 hrs by HPLC-MS/MS analysis		1	ALA3817782	small-molecule physicochemical format	Scientific Literature
12.	ALA3821498	Functional	Antitumor activity against mouse LLC cells xenografted in C57BL/6 mouse assessed as tumor growth inhibition at 7.5 mg/kg administered as oral gavage for 7 days daily relative to vehicle-treated control	Mus musculus	2	ALA3817782	organism-based format	Scientific Literature
13.	ALA3821500	Toxicity	Toxicity in C57BL/6 mouse xenografted with mouse LLC cells assessed as effect on body weight at 7.5 mg/kg administered as oral gavage for 7 days daily	Mus musculus	2	ALA3817782	organism-based format	Scientific Literature
14.	ALA3821501	Toxicity	Toxicity in C57BL/6 mouse xenografted with mouse LLC cells assessed as effect on clinical parameters at 7.5 mg/kg administered as oral gavage for 7 days daily	Mus musculus	2	ALA3817782	organism-based format	Scientific Literature
15.	ALA3821502	ADME	Plasma concentration in C57BL/6 mouse at 7.5 mg/kg administered as single dose measured after 30 mins	Mus musculus	2	ALA3817782	organism-based format	Scientific Literature
16.	ALA4838563	Binding	Trapping activity at FGF in human KMS-11 cells assessed as inhibition of FGFR3 phosphorylation at 6 uM measured after 6 hrs by western blot analysis	Homo sapiens	27	ALA4837219	cell-based format	Scientific Literature
17.	ALA4838574	ADME	Total plasma concentration in NOD-SCID mouse at 7.5 mg/kg, ip measured after 90 mins by HPLC/MS/MS analysis	Mus musculus	4	ALA4837219	organism-based format	Scientific Literature