| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3824676 | F | Antipsychotic activity in mouse at 30 mg/kg, ip administered 15 mins prior to testing by SmartCube automated system based method relative to standard compound | Mus musculus | 9 | organism-based format | Scientific Literature | ||
| 2. | ALA3824677 | B | Displacement of [3H]methyl-spiperone from human recombinant D2 receptor expressed in HEK293 cells at 10 uM after 60 mins by scintillation counting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA3824678 | B | Inhibition of CYP1A in human liver microsomes assessed as reduction in ethoxyresorufin o-deethylation by fluorescence assay | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 4. | ALA3824679 | A | Inhibition of CYP2C19 in human liver microsomes assessed as reduction in S-mephenytoin 4-hydroxylation by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 5. | ALA3824848 | A | Inhibition of CYP2C9 in human liver microsomes assessed as reduction in tolbutamide 4-hydroxylation by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 6. | ALA3824849 | A | Inhibition of CYP2D6 in human liver microsomes assessed as reduction in dextromethorphan o-demethylation by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 7. | ALA3824850 | A | Inhibition of CYP3A4 in human liver microsomes assessed as reduction in midazolam 1-hydroxylation/testosterone 6beta-hydroxylation by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 8. | ALA3824854 | A | Half life in human liver microsomes at 3 uM in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 9. | ALA3824855 | A | Half life in mouse liver microsomes at 3 uM in presence of NADPH by LC-MS/MS analysis | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
| 10. | ALA3824856 | A | Half life in rat liver microsomes at 3 uM in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
| 11. | ALA3824860 | P | Chemical stability of the compound in 0.01 M HCl at pH 2 after 96 hrs by HPLC analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 12. | ALA3824861 | P | Chemical stability of the compound in 20 mM NH4Ac buffer solution at pH 7.1 after 96 hrs by HPLC analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 13. | ALA3824862 | F | Antipsychotic activity in mouse at 10 mg/kg, ip administered 15 mins prior to testing by SmartCube automated system based method relative to standard compound | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3824863 | B | Displacement of [3H]prazosin from rat cerebral cortex adrenergic alpha1 receptor at 10 uM after 60 mins by scintillation counting analysis | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 15. | ALA3824864 | B | Displacement of [3H]RX 821002 from rat cerebral cortex adrenergic alpha2 receptor at 10 uM after 60 mins by scintillation counting analysis | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 16. | ALA3824865 | B | Displacement of [3H]SCH 23390 from human recombinant D1 receptor expressed in CHO cells at 10 uM after 60 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3824866 | B | Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in HEK293 cells at 10 uM after 60 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3824867 | B | Displacement of [3H]mesulergine from human recombinant 5-HT2B receptor expressed in CHO cells at 10 uM after 60 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3824868 | B | Displacement of [3H]BRL 43694 from human recombinant 5-HT3 receptor expressed in CHO cells at 10 uM after 120 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3824869 | B | Displacement of [3H]LSD from human recombinant 5-HT6 receptor expressed in CHO cells at 10 uM after 120 mins by scintillation counting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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