# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3826060 | F | Antiproliferative activity against mouse B16-F10-Luc-G5 cells assessed as cell growth inhibition at 15.36 ug/ml measured after 24 hrs by luciferase gene assay relative to DMSO control | Mus musculus | 46 | ALA3822427 | cell-based format | Scientific Literature | |
2. | ALA5137245 | F | Antibacterial activity against Staphylococcus aureus ATCC 43300 measured after 18 hrs by two-fold serial dilution method | Staphylococcus aureus | 11 | ALA5136964 | organism-based format | Scientific Literature | |
3. | ALA5137246 | F | Antibacterial activity against Enterococcus faecalis ATCC 51299 measured after 18 hrs by two-fold serial dilution method | Enterococcus faecalis | 11 | ALA5136964 | organism-based format | Scientific Literature | |
4. | ALA5137247 | F | Antiparasitic activity against bloodstream form of Trypanosoma brucei brucei Lister 427 measured after 48 hrs by alamar blue assay | Trypanosoma brucei brucei | 11 | ALA5136964 | organism-based format | Scientific Literature | |
5. | ALA5137248 | F | Antileishmanial activity against Leishmania donovani MHOM/ET/67:LV82 amastigotes infected in BMDM cell measured after 48 hrs by luciferase assay | Leishmania donovani | 2 | ALA5136964 | organism-based format | Scientific Literature | |
6. | ALA5137249 | F | Antitrypanosomal activity against bloodstream form of Trypanosoma congolense IL3000 measured after 48 hrs by alamar blue assay | Trypanosoma congolense | 3 | ALA5136964 | organism-based format | Scientific Literature | |
7. | ALA5137250 | F | Antitrypanosomal activity against Trypanosoma vivax STIB 719 by [3H]-hypoxanthine incorporation assay | Trypanosoma vivax | 3 | ALA5136964 | organism-based format | Scientific Literature | |
8. | ALA5137251 | T | Cytotoxicity against rat L6 cells assessed as reduction in cell viability measured after 69 hrs by alamar blue assay | Rattus norvegicus | 2 | ALA5136964 | cell-based format | Scientific Literature | |
9. | ALA5137252 | B | Binding affinity to DNA (unknown origin) assessed as change in melting temperature at 2:1 compound to DNA ratio by UV-visible spectrophotometry | Not specified | 10 | ALA5136964 | nucleic acid format | Scientific Literature | |
10. | ALA5137253 | F | Antitrypanosomal activity against bloodstream form of diminazene-resistant Trypanosoma congolense DimR measured after 48 hrs by alamar blue assay | Trypanosoma congolense | 3 | ALA5136964 | organism-based format | Scientific Literature | |
11. | ALA5137254 | F | Antitrypanosomal activity against bloodstream form of diminazene-resistant Trypanosoma congolense EMS MUT DimR measured after 48 hrs by alamar blue assay | Trypanosoma congolense | 3 | ALA5136964 | organism-based format | Scientific Literature | |
12. | ALA5137255 | F | Resistance factor, ratio of EC50 for bloodstream form of diminazene-resistant Trypanosoma congolense DimR to EC50 for bloodstream form of wild-type Trypanosoma congolense | 3 | ALA5136964 | assay format | Scientific Literature | ||
13. | ALA5137256 | F | Resistance factor, ratio of EC50 for bloodstream form of diminazene-resistant Trypanosoma congolense EMS MUT DimR to EC50 for wild-type bloodstream form of Trypanosoma congolense | 3 | ALA5136964 | assay format | Scientific Literature | ||
14. | ALA5137257 | F | Antiparasitic activity against bloodstream form of tbat1-/- deficient Trypanosoma brucei brucei measured after 48 hrs by alamar blue assay | Trypanosoma brucei brucei | 3 | ALA5136964 | organism-based format | Scientific Literature | |
15. | ALA5137258 | F | Antiparasitic activity against bloodstream form of Trypanosoma brucei brucei B48 measured after 48 hrs by alamar blue assay | Trypanosoma brucei brucei | 3 | ALA5136964 | organism-based format | Scientific Literature | |
16. | ALA5137259 | F | Resistance factor, ratio of EC50 for bloodstream form of tbat1-/- deficient Trypanosoma brucei brucei to EC50 for wild-type bloodstream form of Trypanosoma brucei brucei | 3 | ALA5136964 | assay format | Scientific Literature | ||
17. | ALA5137260 | F | Resistance factor, ratio of EC50 for bloodstream form of Trypanosoma brucei brucei B48 to EC50 for wild-type bloodstream form of Trypanosoma brucei brucei | 3 | ALA5136964 | assay format | Scientific Literature | ||
18. | ALA5137261 | P | Aggregation property of compound in 0.1 M pH 5 sodium acetate buffer at 1.5 mM by 1H-NMR spectra analysis | 2 | ALA5136964 | small-molecule physicochemical format | Scientific Literature | ||
19. | ALA5137262 | P | Aggregation property of compound in 100% DMSO-d6 at 1.5 mM by 1H-NMR spectra analysis | 2 | ALA5136964 | small-molecule physicochemical format | Scientific Literature | ||
20. | ALA5137263 | P | Aggregation property of compound in 45% DMSO-d6:55% 0.1 M pH 5 sodium acetate buffer at 1.5 mM by 1H-NMR spectra analysis | 2 | ALA5136964 | small-molecule physicochemical format | Scientific Literature |