| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3825093 | B | Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-8 and human EAAT3 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluo-4 AM dye based fluorescence imaging plate reader method | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA3825094 | B | Antagonist activity at human iGluA1 receptor flop isoform expressed in CHO-S cells coexpressing TARP gamma-2 assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluo-4 AM dye based fluorescence imaging plate reader method | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 3. | ALA3825097 | B | Antagonist activity at human iGluA1 receptor flip isoform expressed in CHO-S cells assessed as inhibition of glutamate-induced increase in intracellular calcium levels after 2 mins followed by cyclothiazide/glutamate addition by fluo-4 NW dye based fluorescence imaging plate reader method | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 4. | ALA3825099 | A | Drug metabolism in human liver microsomes assessed as oxidative metabolite formation | Homo sapiens | 14 | tissue-based format | Scientific Literature | ||
| 5. | ALA3825100 | A | Drug metabolism in rat liver microsomes assessed as oxidative metabolite formation | Rattus norvegicus | 14 | tissue-based format | Scientific Literature | ||
| 6. | ALA3825105 | A | Clearance in rat | Rattus norvegicus | 14 | organism-based format | Scientific Literature | ||
| 7. | ALA3825110 | A | Inhibition of human CYP1A2 | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 8. | ALA3825111 | A | Induction of CYP1A2 in human hepatocytes at 0.2 to 20 uM compared to omeprazole | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA3825279 | A | Drug metabolism in human hepatocytes assessed as oxidative metabolite formation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3825281 | A | Drug metabolism in rat hepatocytes assessed as oxidative metabolite formation | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3825282 | A | Drug metabolism in human hepatocytes assessed as glucuronidation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3825283 | A | Drug metabolism in rat hepatocytes assessed as glucuronidation | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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