# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3826014 | Binding | Inhibition of recombinant PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins | Homo sapiens | 7 | ALA3822399 | single protein format | Scientific Literature | |
2. | ALA3826017 | Binding | Inhibition of human TCPTP using pNPP as substrate at 25 uM incubated for 30 mins relative to control | Homo sapiens | 1 | ALA3822399 | single protein format | Scientific Literature | |
3. | ALA3826019 | Binding | Inhibition of human SHP1 using pNPP as substrate at 25 uM incubated for 30 mins relative to control | Homo sapiens | 1 | ALA3822399 | single protein format | Scientific Literature | |
4. | ALA3826021 | Binding | Inhibition of human SHP2 using pNPP as substrate at 25 uM incubated for 30 mins relative to control | Homo sapiens | 2 | ALA3822399 | single protein format | Scientific Literature | |
5. | ALA3826023 | Binding | Inhibition of human LAR using pNPP as substrate at 25 uM incubated for 30 mins relative to control | Homo sapiens | 2 | ALA3822399 | single protein format | Scientific Literature | |
6. | ALA3826029 | Binding | Inhibition of PTP1B in rat L6 cells assessed as increase in insulin-stimulated 2-NBDG uptake at 5 uM preincubated for 4 hrs followed by insulin stimulation for 10 mins and subsequent addition of 2-NBDG measured after 30 mins by fluorescence assay relative to control | Rattus norvegicus | 2 | ALA3822399 | cell-based format | Scientific Literature | |
7. | ALA3826030 | Binding | Inhibition of PTP1B in rat L6 cells assessed as increase in insulin-stimulated 2-NBDG uptake at 10 uM preincubated for 4 hrs followed by insulin stimulation for 10 mins and subsequent addition of 2-NBDG measured after 30 mins by fluorescence assay relative to control | Rattus norvegicus | 2 | ALA3822399 | cell-based format | Scientific Literature | |
8. | ALA3826031 | Binding | Inhibition of PTP1B in rat L6 cells assessed as increase in insulin-stimulated 2-NBDG uptake at 20 uM preincubated for 4 hrs followed by insulin stimulation for 10 mins and subsequent addition of 2-NBDG measured after 30 mins by fluorescence assay relative to control | Rattus norvegicus | 2 | ALA3822399 | cell-based format | Scientific Literature |