# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3826003 | B | Inhibition of GST-tagged TAK1 (unknown origin) expressed in sf9 cells coexpressing His-tagged TAB1 using myelin basic protein as substrate incubated for 30 mins in presence of [33P]ATP by microbeta scintillation counting method | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
2. | ALA3826081 | A | Intrinsic clearance in human liver microsomes at 1 uM after 30 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
3. | ALA3826082 | A | Intrinsic clearance in mouse liver microsomes at 1 uM after 30 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
4. | ALA3826083 | A | Drug metabolism in human liver cytosol at 1 uM assessed as N-(2-Methoxy-4-((3-(4-methylpiperazin-1-yl)propyl)carbamoyl)phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide formation after 30 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
5. | ALA3826084 | A | Drug metabolism in mouse liver cytosol at 1 uM assessed as N-(2-Methoxy-4-((3-(4-methylpiperazin-1-yl)propyl)carbamoyl)phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide formation after 30 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 1 | assay format | Scientific Literature | ||
6. | ALA3826087 | A | Solubility in fasted state simulated intestinal fluid irradiated ultrasonically for 10 mins followed by incubation for 24 hrs by HPLC-UV analysis | 4 | assay format | Scientific Literature | |||
7. | ALA3826088 | P | Solubility in 50 mM phosphate buffer at pH 6.5 irradiated ultrasonically for 10 mins followed by incubation for 24 hrs by HPLC-UV analysis | 4 | small-molecule physicochemical format | Scientific Literature |