| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3826557 | B | Inhibition of recombinant FLAG-tagged TAK1 kinase domain (unknown origin) expressed in baculovirus expression system coexpressing TAB using biotin-labeled MKK6kd substrate incubated for 1 hr by AlphaScreen assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA4412490 | B | Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system using fluorescence-labeled substrate by off-chip mobility shift assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 3. | ALA4412492 | B | Inhibition of recombinant FLAG-tagged TAK1 (unknown origin) co-expressed with TAB (unknown origin) in baculovirus using BT-MKK as substrate after 1 hr by AlphaScreen assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4412494 | B | Inhibition of TAK1 (unknown origin) at 1 uM by LanthaScreen Eu kinase binding assay relative to control | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 5. | ALA4412495 | B | Inhibition of TAK1 (unknown origin) at 0.1 uM by LanthaScreen Eu kinase binding assay relative to control | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 6. | ALA4412496 | F | Growth inhibition of human SKCO1 cells after 96 hrs by SRB assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4412497 | F | Growth inhibition of human SW620 cells after 96 hrs by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4412498 | F | Growth inhibition of human LoVo cells after 96 hrs by SRB assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4412531 | T | Toxicity in CAnN.Cg-Foxnlnu/Crljbgi nude mouse xenografted with human SW620 cells assessed as weight loss at 30 mg/kg, po dosed daily for 14 consecutive days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4412533 | F | Antitumor activity against human SW620 cells xenografted in CAnN.Cg-Foxnlnu/Crljbgi nude mouse assessed as tumor growth inhibition at 30 mg/kg, po dosed daily for 14 consecutive days | Homo sapiens | 1 | organism-based format | Scientific Literature |
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