| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4478710 | B | Inhibition of TMP/methicillin-resistant Staphylococcus aureus wild type DHFR assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihydrofolate substrate addition | Staphylococcus aureus | 13 | single protein format | Scientific Literature | ||
| 2. | ALA4478711 | B | Inhibition of TMP/methicillin-resistant Staphylococcus aureus recombinant DHFR F98Y mutant expressed in Escherichia coli BL21 (DE3) cells assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihydrofolate substrate addition | Staphylococcus aureus | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA4478712 | B | Inhibition of TMP/methicillin-resistant Staphylococcus aureus recombinant DHFR H30N mutant expressed in Escherichia coli BL21 (DE3) cells assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihydrofolate substrate addition | Staphylococcus aureus | 13 | cell-based format | Scientific Literature | ||
| 4. | ALA4478713 | B | Inhibition of TMP/methicillin-resistant Staphylococcus aureus recombinant DHFR H149R mutant expressed in Escherichia coli BL21 (DE3) cells assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihydrofolate substrate addition | Staphylococcus aureus | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4478714 | B | Inhibition of TMP/methicillin-resistant Staphylococcus aureus recombinant DHFR H30N/F98Y double mutant expressed in Escherichia coli BL21 (DE3) cells assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihydrofolate substrate addition | Staphylococcus aureus | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA4478715 | B | Inhibition of TMP/methicillin-resistant Staphylococcus aureus recombinant DHFR F98Y/H149R double mutant expressed in Escherichia coli BL21 (DE3) cells assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihydrofolate substrate addition | Staphylococcus aureus | 13 | cell-based format | Scientific Literature | ||
| 7. | ALA4478716 | F | Antibacterial activity against TMP/methicillin-resistant Staphylococcus aureus ATCC 43300 after 18 hrs by CLSI M100-S16 method | Staphylococcus aureus | 13 | organism-based format | Scientific Literature | ||
| 8. | ALA4478717 | F | Antibacterial activity against TMP/methicillin-resistant Staphylococcus aureus harboring DHFR F98Y mutant after 18 hrs by CLSI M100-S16 method | Staphylococcus aureus | 13 | organism-based format | Scientific Literature | ||
| 9. | ALA4478718 | F | Antibacterial activity against TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H30N mutant after 18 hrs by CLSI M100-S16 method | Staphylococcus aureus | 13 | organism-based format | Scientific Literature | ||
| 10. | ALA4478719 | F | Antibacterial activity against TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H149R mutant after 18 hrs by CLSI M100-S16 method | Staphylococcus aureus | 13 | organism-based format | Scientific Literature | ||
| 11. | ALA4478720 | F | Antibacterial activity against TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H30N/F98Y double mutant after 18 hrs by CLSI M100-S16 method | Staphylococcus aureus | 13 | organism-based format | Scientific Literature | ||
| 12. | ALA4478721 | F | Antibacterial activity against TMP/methicillin-resistant Staphylococcus aureus harboring DHFR F98Y/H149R double mutant after 18 hrs by CLSI M100-S16 method | Staphylococcus aureus | 13 | organism-based format | Scientific Literature | ||
| 13. | ALA4478725 | F | Ratio of MIC for TMP/methicillin-resistant Staphylococcus aureus ATCC 43300 in presence of thymidine to MIC for TMP/methicillin-resistant Staphylococcus aureus ATCC 43300 in absence of thymidine | Staphylococcus aureus | 12 | organism-based format | Scientific Literature | ||
| 14. | ALA4478726 | F | Ratio of MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR F98Y mutant in presence of thymidine to MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR F98Y mutant in absence of thymidine | Staphylococcus aureus | 12 | organism-based format | Scientific Literature | ||
| 15. | ALA4478727 | F | Ratio of MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H30N mutant in presence of thymidine to MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H30N mutant in absence of thymidine | Staphylococcus aureus | 12 | organism-based format | Scientific Literature | ||
| 16. | ALA4478728 | F | Ratio of MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H149R mutant in presence of thymidine to MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H149R mutant in absence of thymidine | Staphylococcus aureus | 12 | organism-based format | Scientific Literature | ||
| 17. | ALA4478729 | F | Ratio of MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H30N/F98Y double mutant in presence of thymidine to MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR H30N/F98Y double mutant in absence of thymidine | Staphylococcus aureus | 12 | organism-based format | Scientific Literature | ||
| 18. | ALA4478730 | F | Ratio of MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR F98Y/H149R double mutant in presence of thymidine to MIC for TMP/methicillin-resistant Staphylococcus aureus harboring DHFR F98Y/H149R double mutant in absence of thymidine | Staphylococcus aureus | 12 | organism-based format | Scientific Literature | ||
| 19. | ALA5234351 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv | Mycobacterium tuberculosis | 9 | organism-based format | Scientific Literature | ||
| 20. | ALA5234352 | B | Inhibition of Mycobacterium tuberculosis DHFR | Mycobacterium tuberculosis | 8 | single protein format | Scientific Literature |
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