#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3882295	Binding	Displacement of [3H]-NMS from human recombinant M3 receptor expressed in CHO cell membranes measured after 60 mins by topcount liquid scintillation counting	Homo sapiens	2	ALA3882243	cell-based format	Patent Bioactivity Data
2.	ALA3882296	Functional	Antagonist activity at human recombinant M2 receptor expressed in CHO cells assessed as blocking of muscarinic receptor agonist oxotremorine-induced inhibition of forskolin-mediated cAMP accumulation incubated for 10 mins by topcount liquid scintillation counting	Homo sapiens	1	ALA3882243	cell-based format	Patent Bioactivity Data
3.	ALA3882297	Functional	Antagonist activity at human recombinant M2 receptor expressed in CHO cell membranes assessed as inhibition of oxotremorine-stimulated [35S]GTPgammaS binding incubated for 60 mins by topcount liquid scintillation counting	Homo sapiens	1	ALA3882243	cell-based format	Patent Bioactivity Data
4.	ALA3882298	Functional	Antagonist activity at human recombinant M3 receptor expressed in CHO cells assessed as inhibition of oxotremorine-stimulated intracellular calcium release preincubated for 20 mins followed by oxotremorine addition measured every 0.5 to 1 secs for 15 mins by fluo-4AM dye based FLIPR assay	Homo sapiens	1	ALA3882243	cell-based format	Patent Bioactivity Data
5.	ALA3882299	Functional	Bronchoprotective activity in Dunkan-Hartley guinea pig model of acetylcholine-induced bronchoconstriction assessed as efficacious dose that limited bronchrestriction response to 50 ug/mL dose of acetylcholine to doubling of baseline pulmonary resistance administered via nebulization for 10 mins measured at 1.5 hrs post dose by whole body plethysmography	Cavia porcellus	1	ALA3882243	assay format	Patent Bioactivity Data
6.	ALA3882300	Functional	Apparent lung selectivity index, ratio of ID50 for inhibition of pilocarpine-induced salivation in guinea pig administered via nebulization for 10 mins to ID50 for bronchoprotective activity in Dunkan-Hartley guinea pig assessed as inhibition of acetylcholine-induced bronchoconstriction administered via nebulization for 10 mins	Cavia porcellus	1	ALA3882243	assay format	Patent Bioactivity Data
7.	ALA3882301	Functional	Apparent lung selectivity index, ratio of ID50 for inhibition of methacholine-induced depressor response in guinea pig administered via nebulization for 10 mins to ID50 for bronchoprotective activity in Dunkan-Hartley guinea pig assessed as inhibition of acetylcholine-induced bronchoconstriction administered via nebulization for 10 mins	Cavia porcellus	1	ALA3882243	assay format	Patent Bioactivity Data
8.	ALA4495582	Functional	SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate	Severe acute respiratory syndrome coronavirus 2	7,212	ALA4495564	assay format	SARS-CoV-2 Screening Data 2020-21
9.	ALA4513082	Functional	Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging	Chlorocebus sabaeus	7,212	ALA4495565	organism-based format	SARS-CoV-2 Screening Data 2020-21
10.	ALA4650107	Binding	Thermal Shift Assay. Domain start/stop: M626-G740	Homo sapiens	1,014	ALA4649998	single protein format	EUbOPEN Chemogenomic Library
11.	ALA4725212	Toxicity	Incucyte cell viability with HEK293T	Homo sapiens	1,713	ALA4689842	cell-based format	EUbOPEN Chemogenomic Library
12.	ALA4725213	Toxicity	Incucyte cell viability with human fibroblast	Homo sapiens	1,718	ALA4689842	cell-based format	EUbOPEN Chemogenomic Library
13.	ALA4725214	Toxicity	Incucyte cell viability with U2OS	Homo sapiens	1,712	ALA4689842	cell-based format	EUbOPEN Chemogenomic Library
14.	ALA5060015	Binding	Thermal Shift Assay. Domain: start/stop: S229-K512	Homo sapiens	1,499	ALA5060014	single protein format	EUbOPEN Chemogenomic Library
15.	ALA5060944	Binding	Thermal Shift Assay. Domain: start/stop: N44-E168	Homo sapiens	1,502	ALA5060014	single protein format	EUbOPEN Chemogenomic Library
16.	ALA5062802	Binding	Thermal Shift Assay. Domain: start/stop: M1-L298	Homo sapiens	1,499	ALA5060014	single protein format	EUbOPEN Chemogenomic Library
17.	ALA5063731	Binding	Thermal Shift Assay. Domain: start/stop: M1-K294	Homo sapiens	1,499	ALA5060014	single protein format	EUbOPEN Chemogenomic Library
18.	ALA5064660	Binding	Thermal Shift Assay. Domain: start/stop: P449-E759	Homo sapiens	1,499	ALA5060014	single protein format	EUbOPEN Chemogenomic Library
19.	ALA5065589	Binding	Thermal Shift Assay. Domain: start/stop: M26-R383	Homo sapiens	1,499	ALA5060014	single protein format	EUbOPEN Chemogenomic Library
20.	ALA5066518	Binding	Thermal Shift Assay. Domain: start/stop: M1-S360	Homo sapiens	1,499	ALA5060014	single protein format	EUbOPEN Chemogenomic Library