# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3830286 | B | Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
2. | ALA3830287 | B | Inhibition of PSMA (unknown origin) assessed as reduction in glutamate formation using NAAG as substrate preincubated for 30 mins followed by substrate addition by Amplex red assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
3. | ALA3830288 | A | Drug uptake in human PC3-ML cells expressing PSMA at 10 to 1000 nM after 4 hrs by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA3830289 | A | Drug uptake in human PC3-ML cells expressing hepsin at 100 to 1000 nM after 4 hrs by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA3830290 | A | Drug uptake in human PC3-ML cells expressing hepsin/PSMA at 100 to 1000 nM after 4 hrs by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA3830291 | A | Drug uptake in tumor of NOD/Shi-scid/IL-2Rgamma null mouse xenografted with human PC3-ML cells expressing PSMA at 1 nmol, iv measured 24 hrs post dosing by near infrared optical imaging analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA3830292 | A | Drug uptake in tumor of NOD/Shi-scid/IL-2Rgamma null mouse xenografted with human PC3-ML cells expressing PSMA/HPN at 1 nmol, iv measured 24 hrs post dosing by near infrared optical imaging analysis | Mus musculus | 1 | organism-based format | Scientific Literature |