# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3875318 | Binding | Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling activity using relaxed pBR322 as substrate incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis | Mycobacterium tuberculosis | 82 | ALA3875146 | assay format | Scientific Literature | |
2. | ALA3875321 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis incubated for 7 days by alamar blue assay | Mycobacterium tuberculosis | 37 | ALA3875146 | assay format | Scientific Literature | |
3. | ALA3875322 | Toxicity | Cytotoxicity against mouse RAW264.7 cells assessed as inhibition of cell viability at 100 uM measured after 48 hrs by MTT assay relative to control | Mus musculus | 37 | ALA3875146 | organism-based format | Scientific Literature | |
4. | ALA5234560 | Binding | Inhibition of Mycobacterium tuberculosis (MTB) DNA gyrase using pBR322 DNA by supercoiling assay | Mycobacterium tuberculosis | 3 | ALA5233247 | protein complex format | Scientific Literature | |
5. | ALA5234561 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis incubated for 7 days by MABA assay | Mycobacterium tuberculosis | 3 | ALA5233247 | organism-based format | Scientific Literature |