# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA619924 | B | In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined | 57 | cell-based format | Scientific Literature | |||
2. | ALA763074 | B | Inhibition of Prostaglandin G/H synthase activity in sheep seminal vesicle was determined | Ovis aries | 6 | tissue-based format | Scientific Literature | ||
3. | ALA785677 | F | Inhibition of lipid peroxidation in rat liver microsomes at 1 uM | Rattus norvegicus | 18 | organism-based format | Scientific Literature | ||
4. | ALA2015642 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 22 hrs by ELISA | Mus musculus | 7 | cell-based format | Scientific Literature | ||
5. | ALA2015643 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL6 production at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 22 hrs by ELISA | Mus musculus | 7 | cell-based format | Scientific Literature | ||
6. | ALA2015644 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of LPS-induced COX-2 mRNA expression at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 6 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
7. | ALA2015645 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of LPS-induced IL-1beta mRNA expression at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 6 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
8. | ALA2015646 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of LPS-induced IL-12 mRNA expression at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 6 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
9. | ALA2015650 | B | Inhibition of LPS-induced ERK phosphorylation in ICR mouse primary peritoneal macrophages at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 1 hr by Western blot analysis | Mus musculus | 5 | assay format | Scientific Literature | ||
10. | ALA2015651 | B | Inhibition of LPS-induced p38 phosphorylation in ICR mouse primary peritoneal macrophages at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 1 hr by Western blot analysis | Mus musculus | 5 | assay format | Scientific Literature | ||
11. | ALA2015760 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of high glucose-induced TNFalpha mRNA expression at 10 uM incubated for 2 hrs prior to high glucose-challenge measured after 3 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
12. | ALA2015761 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of high glucose-induced IL1beta mRNA expression at 10 uM incubated for 2 hrs prior to high glucose-challenge measured after 3 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
13. | ALA2015762 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of high glucose-induced IL12 mRNA expression at 10 uM incubated for 2 hrs prior to high glucose-challenge measured after 3 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
14. | ALA2015763 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of high glucose-induced IL6 mRNA expression at 10 uM incubated for 2 hrs prior to high glucose-challenge measured after 3 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
15. | ALA2015764 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL6 production incubated for 2 hrs prior to LPS-challenge measured after 22 hrs by ELISA | Mus musculus | 5 | cell-based format | Scientific Literature | ||
16. | ALA2015765 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha production incubated for 2 hrs prior to LPS-challenge measured after 22 hrs by ELISA | Mus musculus | 5 | cell-based format | Scientific Literature | ||
17. | ALA2015766 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of LPS-induced TNF-alpha mRNA expression at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 6 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
18. | ALA2015767 | F | Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as downregulation of LPS-induced IL-6 mRNA expression at 10 uM incubated for 2 hrs prior to LPS-challenge measured after 6 hrs by RT-qPCR analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
19. | ALA3061287 | F | Anti-inflammatory activity in Rattus norvegicus Wistar (rat) assessed as inhibition of carrageenan-induced paw edema at 160 mg/kg, po administered 30 min prior to carrageenan challenge measured at 4 hr relative to control | Rattus norvegicus | 22 | organism-based format | Scientific Literature | ||
20. | ALA3061294 | F | Analgesic activity in Mus musculus Swiss albino (mouse) assessed as inhibition of acetic acid-induced writhing at 160 mg/kg, po administered 30 min prior challenge measured after 5 min of challenge for next 30 min relative to control | Mus musculus | 22 | organism-based format | Scientific Literature |