# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3877543 | B | Agonist activity at human (alpha4beta2 )2beta2 expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assay relative to carbamylcholine | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature | |
2. | ALA3877544 | B | Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | ALA3877245 | protein complex format | Scientific Literature | |
3. | ALA3877546 | B | Displacement of [3H]epibatidine from rat alpha3beta2 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | ALA3877245 | protein complex format | Scientific Literature | |
4. | ALA3877548 | B | Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | ALA3877245 | protein complex format | Scientific Literature | |
5. | ALA3877549 | B | Displacement of [3H]epibatidine from rat forebrain alpha4beta2* nAChR by liquid scintillation counting | Rattus norvegicus | 9 | ALA3877245 | assay format | Scientific Literature | |
6. | ALA3877550 | B | Displacement of [3H]epibatidine from rat alpha4beta4 nAChR by liquid scintillation counting | Rattus norvegicus | 9 | ALA3877245 | protein complex format | Scientific Literature | |
7. | ALA3877551 | B | Displacement of [3H]epibatidine from rat forebrain alpha7* nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 9 | ALA3877245 | assay format | Scientific Literature | |
8. | ALA3877552 | B | Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assay | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature | |
9. | ALA3877553 | B | Antagonist activity at human alpha4beta2 expressed in human SH-EP1 cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated for 10 mins followed by carbamylcholine addition measured after 5 mins by Cherenkov counting | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature | |
10. | ALA3877556 | B | Agonist activity at human (alpha4beta2 )2alpha4 expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assay relative to carbamylcholine | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature | |
11. | ALA3877557 | B | Displacement of [3H]epibatidine from rat alpha7 nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 9 | ALA3877245 | single protein format | Scientific Literature | |
12. | ALA3877558 | A | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 4 | ALA3877245 | protein complex format | Scientific Literature | |
13. | ALA3877559 | B | Displacement of [3H]epibatidine from rat alpha2beta4 nAChR at 10 uM by liquid scintillation counting | Rattus norvegicus | 2 | ALA3877245 | protein complex format | Scientific Literature | |
14. | ALA3877561 | U | Selectivity ratio of Ki for rat alpha3beta4 nAChR to Ki for rat alpha4beta2 nAChR | Rattus norvegicus | 3 | ALA3877245 | assay format | Scientific Literature | |
15. | ALA3877562 | A | Agonist activity at alpha3beta4* nAChR in human SH-SY5Y cells after 9.5 mins by 86Rb+ efflux assay | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature | |
16. | ALA3877563 | A | Antagonist activity at alpha3beta4* in human SH-SY5Y cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated for 10 mins followed by carbamylcholine addition measured after 5 mins by Cherenkov counting | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature | |
17. | ALA3877564 | B | Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assay | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature | |
18. | ALA3877565 | B | Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated for 10 mins followed by carbamylcholine addition measured after 5 mins by Cherenkov counting | Homo sapiens | 7 | ALA3877245 | cell-based format | Scientific Literature |