# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3863299 | F | Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of human CCL27-dependent calcium flux in presence of coelenterazine H by chemiluminescence assay | Homo sapiens | 42 | ALA3862010 | cell-based format | Scientific Literature | |
2. | ALA3863300 | B | Antagonist activity at human CCR10 expressed in mouse BA/F3 cells assessed as inhibition of human CCL27-dependent chemotaxis | Homo sapiens | 11 | ALA3862010 | cell-based format | Scientific Literature | |
3. | ALA3863301 | F | Antagonist activity at mouse CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of CCL27-dependent calcium flux in presence of coelenterazine H by chemiluminescence assay | Mus musculus | 10 | ALA3862010 | cell-based format | Scientific Literature | |
4. | ALA3863302 | F | Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of CCL27-dependent calcium flux in presence of coelenterazine H by FLIPR assay | Homo sapiens | 4 | ALA3862010 | cell-based format | Scientific Literature | |
5. | ALA3863304 | F | Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of human CCL28-dependent calcium flux by FLIPR assay | Homo sapiens | 3 | ALA3862010 | cell-based format | Scientific Literature | |
6. | ALA3863305 | F | Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of human CCL28-dependent calcium flux by chemiluminescence assay | Homo sapiens | 3 | ALA3862010 | cell-based format | Scientific Literature | |
7. | ALA3863306 | F | Antagonist activity at human CCR10 expressed in HEK cells assessed as inhibition of human CCL27-dependent cAMP production | Homo sapiens | 2 | ALA3862010 | cell-based format | Scientific Literature | |
8. | ALA3863307 | A | Protein binding in Balb/C mouse plasma at 100 mg/kg, ip bid | Mus musculus | 1 | ALA3862010 | organism-based format | Scientific Literature | |
9. | ALA3863308 | A | Half life in mouse liver microsomes | Mus musculus | 1 | ALA3862010 | tissue-based format | Scientific Literature | |
10. | ALA3863309 | B | Antagonist activity at human CCR10 expressed in HEK cell membranes assessed as inhibition of human CCL27-dependent europium-labeled GTP binding | Homo sapiens | 2 | ALA3862010 | cell-based format | Scientific Literature | |
11. | ALA3863310 | F | Antagonist activity at human CCR1 assessed as inhibition of MIP1alpha-induced calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
12. | ALA3863311 | F | Antagonist activity at human CCR2 assessed as inhibition of MCP1-induced calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
13. | ALA3863312 | F | Antagonist activity at human CCR5 assessed as inhibition of RANTES-induced calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
14. | ALA3863313 | F | Antagonist activity at human CXCR3 assessed as inhibition of IP10-induced calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
15. | ALA3863314 | F | Antagonist activity at human CXCR2 assessed as inhibition of GROalpha-induced calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
16. | ALA3863315 | F | Antagonist activity at human CCR6 assessed as inhibition of CCL20/MIP-3alpha-induced calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
17. | ALA3863316 | F | Antagonist activity at human histamine H4 receptor assessed as inhibition of histamine-induced calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
18. | ALA3863317 | F | Agonist activity at human CCR1 assessed as induction of calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
19. | ALA3863318 | F | Agonist activity at human CCR2 assessed as induction of calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature | |
20. | ALA3863319 | F | Agonist activity at human CCR5 assessed as induction of calcium flux | Homo sapiens | 2 | ALA3862010 | single protein format | Scientific Literature |