| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3871091 | Physicochemical | Kinetic solubility of compound in PBS buffer at pH 7.4 after 1 hr by micro-plate nephelometric analysis | 3 | ALA3870349 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA3871092 | Binding | Inhibition of human EZH1 complex using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysis | Homo sapiens | 11 | ALA3870349 | single protein format | Scientific Literature | |
| 3. | ALA3871093 | Binding | Inhibition of human EZH2 Y641F mutant using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysis | Homo sapiens | 11 | ALA3870349 | assay format | Scientific Literature | |
| 4. | ALA3871094 | Binding | Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysis | Homo sapiens | 15 | ALA3870349 | single protein format | Scientific Literature | |
| 5. | ALA3871095 | ADME | Oxidative metabolic stability in human liver microsomes assessed as amount of parent compound remaining at 1 uM after 30 mins by LC-MS/MS | Homo sapiens | 3 | ALA3870349 | tissue-based format | Scientific Literature | |
| 6. | ALA3871096 | ADME | Oxidative metabolic stability in mouse liver microsomes assessed as amount of parent compound remaining at 1 uM after 30 mins by LC-MS/MS | Mus musculus | 3 | ALA3870349 | tissue-based format | Scientific Literature | |
| 7. | ALA3871097 | Binding | Resistance index, ratio of IC50 for human EZH2 Y641F mutant to IC50 for human wild type EZH2 | Homo sapiens | 11 | ALA3870349 | assay format | Scientific Literature |
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