# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3861037 | A | Induction of CYP1A1 expression in human primary hepatocytes at 1 uM incubated for 48 hrs by RT-PCR method | Homo sapiens | 1 | ALA3860060 | cell-based format | Scientific Literature | |
2. | ALA3861042 | B | Inhibition of cat NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Felis catus | 1 | ALA3860060 | cell-based format | Scientific Literature | |
3. | ALA3861043 | B | Inhibition of pig NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Felis catus | 1 | ALA3860060 | cell-based format | Scientific Literature | |
4. | ALA3861044 | B | Inhibition of rat NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Rattus norvegicus | 1 | ALA3860060 | cell-based format | Scientific Literature | |
5. | ALA3861045 | B | Selectivity index, ratio of IC50 for human NHE1 to IC50 for human NHE3 | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
6. | ALA3861046 | B | Selectivity index, ratio of IC50 for human NHE2 to IC50 for human NHE3 | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
7. | ALA3861047 | B | Inhibition of human NHE1 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Homo sapiens | 1 | ALA3860060 | cell-based format | Scientific Literature | |
8. | ALA3861048 | B | Inhibition of human NHE2 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Homo sapiens | 1 | ALA3860060 | cell-based format | Scientific Literature | |
9. | ALA3861049 | B | Selectivity index, ratio of IC50 for human NHE5 to IC50 for human NHE3 | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
10. | ALA3861050 | B | Inhibition of human NHE5 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assay | Homo sapiens | 1 | ALA3860060 | cell-based format | Scientific Literature | |
11. | ALA3861051 | B | Inhibition of GABA-gated chloride channel (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
12. | ALA3861052 | B | Inhibition of PDE4 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
13. | ALA3861053 | B | Inhibition of GABA-gated chloride channel (unknown origin) | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
14. | ALA3861054 | B | Inhibition of PDE4 (unknown origin) | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
15. | ALA3861055 | A | Drug metabolism in human hepatic microsomes assessed as compound lability by LC-MS/MS method | Homo sapiens | 1 | ALA3860060 | assay format | Scientific Literature | |
16. | ALA3861056 | A | Drug metabolism in rat hepatic microsomes assessed as compound lability by LC-MS/MS method | Rattus norvegicus | 1 | ALA3860060 | assay format | Scientific Literature | |
17. | ALA3861057 | A | Drug metabolism in mouse hepatic microsomes assessed as compound lability by LC-MS/MS method | Mus musculus | 1 | ALA3860060 | assay format | Scientific Literature | |
18. | ALA3861058 | A | Drug metabolism in guinea pig hepatic microsomes assessed as compound lability by LC-MS/MS method | Cavia porcellus | 1 | ALA3860060 | assay format | Scientific Literature | |
19. | ALA3861059 | A | Drug metabolism in rabbit hepatic microsomes assessed as compound lability by LC-MS/MS method | Oryctolagus cuniculus | 1 | ALA3860060 | assay format | Scientific Literature | |
20. | ALA3861060 | A | Drug metabolism in Landrance pig hepatic microsomes assessed as compound lability by LC-MS/MS method | Sus scrofa | 1 | ALA3860060 | assay format | Scientific Literature |