| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3867372 | B | Inhibition of Toxoplasma gondii TS-DHFR expressed in Escherichia coli BL21 preincubated for 15 mins followed by addition of DHF as substrate and NADPH measured after 60 mins by resazurin/diaphorase coupled assay | Toxoplasma gondii | 24 | cell-free format | Scientific Literature | ||
| 2. | ALA3867373 | A | Inhibition of recombinant human DHFR expressed in Escherichia coli preincubated for 15 mins followed by addition of DHF as substrate and NADPH measured after 60 mins by resazurin/diaphorase coupled assay | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 3. | ALA3867374 | B | Selectivity ratio of IC50 for human DHFR to IC50 for Toxoplasma gondii DHFR | 24 | assay format | Scientific Literature |
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