| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3857969 | A | Cmax in CD-1 mouse brain at 10 mg/kg, ip administered as single dose after 30 mins by LC/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA3857970 | A | Elimination half life in CD-1 mouse plasma at 10 mg/kg, ip administered as single dose by LC/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA3857971 | B | Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cell membranes after 1 hr by microbeta counting analysis | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 4. | ALA3857972 | B | Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cell membranes after 1 hr by microbeta counting analysis | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 5. | ALA3857973 | B | Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membranes after 1 hr by microbeta counting analysis | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 6. | ALA3857974 | B | Displacement of [3H]raclopride from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by microbeta counting analysis | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 7. | ALA3857975 | A | Displacement of [3H]-prazosin from adrenergic alpha 1 receptor in pig brain cortical membranes after 50 mins by microbeta counting analysis | Sus scrofa | 33 | cell membrane format | Scientific Literature | ||
| 8. | ALA3857976 | A | Stability in mouse liver microsomes assessed as oxidative metabolism by measuring drug recovery at 10 uM preincubated for 10 mins followed by NADPH addition measured after 30 mins by liquid chromatographic method | Mus musculus | 40 | tissue-based format | Scientific Literature | ||
| 9. | ALA3857983 | A | Half life in mouse liver microsomes in presence of NADPH by liquid chromatographic method | Mus musculus | 6 | tissue-based format | Scientific Literature | ||
| 10. | ALA3857984 | A | Intrinsic clearance in mouse plasma in presence of NADPH by liquid chromatographic method | Mus musculus | 6 | cell-free format | Scientific Literature | ||
| 11. | ALA3857988 | B | Agonist activity at 5-HT7 receptor in embryonic day 15 C57BL/6 mouse striatum assessed as increase in neurite length at 20 nM after 30 mins by DAPI staining based microscopy relative to control | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3857989 | B | Agonist activity at 5-HT7 receptor in embryonic day 15 C57BL/6 mouse striatum assessed as increase in neurite length at 20 nM up to 4 hrs by DAPI staining based microscopy relative to control | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3857993 | B | Agonist activity at 5-HT7 receptor in embryonic day 15 C57BL/6 mouse cortex assessed as increase in neurite length at 20 nM after 30 mins by DAPI staining based microscopy relative to control | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA3857994 | B | Agonist activity at 5-HT7 receptor in embryonic day 15 C57BL/6 mouse cortex assessed as increase in neurite length at 20 nM up to 24 hrs by DAPI staining based microscopy | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 15. | ALA3857995 | B | Agonist activity at 5-HT7 receptor in embryonic day 15 C57BL/6 mouse striatum assessed as increase in neurite length at 20 nM after 2 hrs in presence of 5-HT7 receptor antagonist SB-269970 by DAPI staining based microscopic analysis | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3857997 | B | Agonist activity at 5-HT7 receptor in embryonic day 15 C57BL/6 mouse cortex assessed as increase in neurite length at 20 nM after 2 hrs in presence of 5-HT7 receptor antagonist SB-269970 by DAPI staining based microscopic analysis | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 17. | ALA3857998 | A | Cmax in CD-1 mouse plasma at 10 mg/kg, ip administered as single dose after 30 mins by LC/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3857999 | A | Drug uptake in CD-1 mouse plasma at 10 mg/kg, ip administered as single dose measured up to 4 hrs by LC/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3858000 | A | Elimination half life in CD-1 mouse brain at 10 mg/kg, ip administered as single dose by LC/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3858001 | A | Ratio of drug uptake in CD-1 mouse brain to plasma at 10 mg/kg, ip administered as single dose by LC/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
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